Background Persistent atrial fibrillation (AF) is difficult to treat. In the absence of class I or III
antiarrhythmic drugs sinus rhythm is maintained in only 30% of patients during the first year …

The aim of the study was to evaluate the effect of losartan as compared with amlodipine,
both associated with amiodarone, in preventing the recurrence of atrial fibrillation (AF) in …

Atrial fibrillation is very common in the United States. After a search of Medline, EMBASE,
and CINAHL, 4 trials evaluating inhibitors of the renin‐angiotensin system were identified for …

Introduction: Angiotensin II and Aldosterone are key factors responsible for structural and
electrical atrial remodelling in patients with atrial fibrillation (AF). Hypothesis: Aim of this …

Background The reverse-remodeling effect of angiotensin II type 1 receptor blocker (ARB)
on atrial fibrillation (AF) is unclear. Methods and Results Sustained AF was induced in 20 …

Atrial fibrillation (AF) is a source of considerable morbidity and mortality. There has been
compelling evidence supporting the role of renin‐angiotensin system (RAS) in the genesis …

Background—The effect of verapamil on long-term tachycardia-induced atrial electrical
remodeling has not been reported. Methods and Results—Forty-eight dogs were randomly …

Atrial fibrillation (AF) is the most common clinical arrhythmia, and is difficult to treat. Current
treatment strategies are far from optimal. Antiarrhythmic drug therapy to maintain sinus …

Experimental and human studies have shown how the shortening of atrial refractoriness and
repolarization and abnormal adaptation to rate, the so-called electrical remodeling, increase …

Atrial fibrillation (AF) is known to be an important risk factor for thrombo-embolism. 1, 2 AF
has been shown to induce a prolonged mechanical dysfunction of the atria, which becomes …