Aim Recent scientific evidence has emphasized the possible role of inhibitors of the renin-
angiotensin system in preventing arrhythmic relapses in patients with paroxysmal or …

Abstract Effects of enalapril on a canine model of atrial pacing-induced atrial fibrillation (AF)
with rapid ventricular responses were determined. Methods: Four weeks of atrial rapid …

Objectives To evaluate whether the response to antiarrhythmic drug therapy in patients with
paroxysmal atrial fibrillation affects the development of structural remodeling in the left …

Large clinical trials have demonstrated that angiotensin-converting-enzyme (ACE) inhibitors
are associated with beneficial outcomes in patients with arterial hypertension, heart failure …

Prior experimental and clinical studies have demonstrated that verapamil may attenuate the
atrial electrical remodeling that is induced by atrial fibrillation (AF), 1, 2 thereby reducing the …

Electrical remodeling plays a pivotal role in maintaining the reentry during atrial fibrillation.
In this study, we assessed influence of electrical remodeling on pharmacological …

The heterogeneous process of atrial electrical remodeling (AER) in the canine rapid atrial
stimulation model has been previously reported although it has been reported that a sodium …

Purpose: To assess the effects of amiodarone and diltiazem on atrial fibrillation (AF) induced
atrial electrical remodeling and their clinical implications. Methods: Persistent AF patients …

Background—Left atrial (LA) dilation precedes or appears early after the onset of atrial
fibrillation (AF) and factors in perpetuating the arrhythmia. Angiotensin receptor blockers …

Inhibition of the renin-angiotensin-aldosterone system is a novel concept for the treatment of
atrial fibrillation that may target the underlying substrate of atrial fibrillation. Further human …