The scaling of goals from cellular to anatomical homeostasis: an evolutionary simulation, experiment and analysis

L Pio-Lopez, J Bischof, JV LaPalme… - Interface …, 2023 - royalsocietypublishing.org
Complex living agents consist of cells, which are themselves competent sub-agents
navigating physiological and metabolic spaces. Behaviour science, evolutionary …

The scaling of goals via homeostasis: an evolutionary simulation, experiment and analysis

L Pio-Lopez, J Bischof, JV LaPalme, M Levin - arXiv preprint arXiv …, 2022 - arxiv.org
All cognitive agents are composite beings. Specifically, complex living agents consist of
cells, which are themselves competent sub-agents navigating physiological and metabolic …

[HTML][HTML] Technological approach to mind everywhere: an experimentally-grounded framework for understanding diverse bodies and minds

M Levin - Frontiers in systems neuroscience, 2022 - frontiersin.org
Synthetic biology and bioengineering provide the opportunity to create novel embodied
cognitive systems (otherwise known as minds) in a very wide variety of chimeric …

Technological Approach to Mind Everywhere (TAME): an experimentally-grounded framework for understanding diverse bodies and minds

M Levin - arXiv preprint arXiv:2201.10346, 2021 - arxiv.org
Synthetic biology and bioengineering provide the opportunity to create novel embodied
cognitive systems (otherwise known as minds) in a very wide variety of chimeric …

[HTML][HTML] Competency in navigating arbitrary spaces as an invariant for analyzing cognition in diverse embodiments

C Fields, M Levin - Entropy, 2022 - mdpi.com
One of the most salient features of life is its capacity to handle novelty and namely to thrive
and adapt to new circumstances and changes in both the environment and internal …

[HTML][HTML] Evolution of networks for body plan patterning; interplay of modularity, robustness and evolvability

KH Ten Tusscher, P Hogeweg - PLoS computational biology, 2011 - journals.plos.org
A major goal of evolutionary developmental biology (evo-devo) is to understand how
multicellular body plans of increasing complexity have evolved, and how the corresponding …

[HTML][HTML] A topological look into the evolution of developmental programs

S Mani, T Tlusty - Biophysical Journal, 2021 - cell.com
Rapid advance of experimental techniques provides an unprecedented in-depth view into
complex developmental processes. Still, little is known on how the complexity of multicellular …

[HTML][HTML] Darwin's agential materials: evolutionary implications of multiscale competency in developmental biology

M Levin - Cellular and Molecular Life Sciences, 2023 - Springer
A critical aspect of evolution is the layer of developmental physiology that operates between
the genotype and the anatomical phenotype. While much work has addressed the evolution …

Shapes in the shadow: evolutionary dynamics of morphogenesis

P Hogeweg - Artificial Life, 2000 - ieeexplore.ieee.org
This article investigates the evolutionary dynamics of morphogenesis. In this study,
morphogenesis arises as a side-effect of maximization of number of cell types. Thus, it …

Morphogenesis as Bayesian inference: A variational approach to pattern formation and control in complex biological systems

F Kuchling, K Friston, G Georgiev, M Levin - Physics of life reviews, 2020 - Elsevier
Recent advances in molecular biology such as gene editing [1], bioelectric recording and
manipulation [2] and live cell microscopy using fluorescent reporters [3],[4]–especially with …