Flavonifractor plautii Protects Against Elevated Arterial Stiffness

S Luo, Y Zhao, S Zhu, L Liu, K Cheng, B Ye… - Circulation …, 2023 - Am Heart Assoc
Background: Dysbiosis of gut microbiota plays a pivotal role in vascular dysfunction and
microbial diversity was reported to be inversely correlated with arterial stiffness. However …

Dysbiosis signatures of gut microbiota in coronary artery disease

Q Zhu, R Gao, Y Zhang, D Pan, Y Zhu… - Physiological …, 2018 - journals.physiology.org
Gut microbiota dysbiosis has been considered to be an important risk factor that contributes
to coronary artery disease (CAD), but limited evidence exists about the involvement of gut …

Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study

VD de Mello, J Paananen, J Lindström, MA Lankinen… - Scientific reports, 2017 - nature.com
Wide-scale profiling technologies including metabolomics broaden the possibility of novel
discoveries related to the pathogenesis of type 2 diabetes (T2D). By applying non-targeted …

The emerging role of the gut microbiome in cardiovascular disease: Current knowledge and perspectives

PD Papadopoulos, C Tsigalou, PN Valsamaki… - Biomedicines, 2022 - mdpi.com
The collection of normally non-pathogenic microorganisms that mainly inhabit our gut lumen
shapes our health in many ways. Structural and functional perturbations in the gut microbial …

Cross‐Talk between Gut Microbiota and Heart via the Routes of Metabolite and Immunity

J Bu, Z Wang - Gastroenterology research and practice, 2018 - Wiley Online Library
Considering the prevalence of cardiovascular disease (CVD), significant interest has been
focused on the gut microbiota‐heart interaction because the gut microbiota has been …

The gut microbiota (microbiome) in cardiovascular disease and its therapeutic regulation

MM Rahman, F Islam, MH -Or-Rashid… - Frontiers in cellular …, 2022 - frontiersin.org
In the last two decades, considerable interest has been shown in understanding the
development of the gut microbiota and its internal and external effects on the intestine, as …

Gut microbiota from coronary artery disease patients contributes to vascular dysfunction in mice by regulating bile acid metabolism and immune activation

H Liu, R Tian, H Wang, S Feng, H Li, Y Xiao… - Journal of translational …, 2020 - Springer
Background The gut microbiota was shown to play a crucial role in the development of
vascular dysfunction, and the bacterial composition differed between healthy controls and …

Gut microbiome and cardiovascular disease

Y Zhao, Z Wang - Current opinion in cardiology, 2020 - journals.lww.com
In this review, we discuss the molecular mechanisms of gut microbiome contributing to CVD,
which include gut microbes translocalization to aortic artery because of gut barrier defect to …

[HTML][HTML] A cardiovascular disease-linked gut microbial metabolite acts via adrenergic receptors

I Nemet, PP Saha, N Gupta, W Zhu, KA Romano… - Cell, 2020 - cell.com
Summary Using untargeted metabolomics (n= 1,162 subjects), the plasma metabolite (m/z=
265.1188) phenylacetylglutamine (PAGln) was discovered and then shown in an …

[HTML][HTML] Role of butyrate, a gut microbiota derived metabolite, in cardiovascular diseases: A comprehensive narrative review

P Amiri, SA Hosseini, S Ghaffari, H Tutunchi… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular diseases (CVD) are major causes of death worldwide. Recently, new roles
for intestinal microbiota in pathology and treatment of CVD have been proposed. Butyrate, a …