Treating inflammation associated with pulmonary hypertension: an overview of the literature

HHB Yoo, FL Marin - International Journal of General Medicine, 2022 - Taylor & Francis
Pulmonary hypertension (PH) comprises five groups of serious clinical entities characterized
by pulmonary artery vasoconstriction and vascular remodeling leading to right heart failure …

Disease-specific platelet signaling defects in idiopathic pulmonary arterial hypertension

KS Aulak, S Al Abdi, L Li, JS Crabb… - … of Physiology-Lung …, 2021 - journals.physiology.org
Idiopathic pulmonary arterial hypertension (IPAH) is a rapidly progressive disease with
several treatment options. Long-term mortality remains high with great heterogeneity in …

[HTML][HTML] Mechanisms of disease: pulmonary arterial hypertension

RT Schermuly, HA Ghofrani, MR Wilkins… - Nature Reviews …, 2011 - nature.com
Our understanding of, and approach to, pulmonary arterial hypertension has undergone a
paradigm shift in the past decade. Once a condition thought to be dominated by increased …

Treatment of pulmonary arterial hypertension: recent progress and a look to the future

M Humbert, O Sitbon, C Guignabert… - The Lancet …, 2023 - thelancet.com
Pulmonary arterial hypertension (PAH) is a severe but treatable form of pre-capillary
pulmonary hypertension caused by pulmonary vascular remodelling. As a result of basic …

Molecular pathogenesis of pulmonary arterial hypertension

M Rabinovitch - The Journal of clinical investigation, 2008 - Am Soc Clin Investig
Recent investigations have suggested that it might be possible to reverse the pathology of
pulmonary arterial hypertension (PAH), a disorder that can be rapidly progressive and fatal …

Pulmonary arterial hypertension: new ideas and perspectives

N Galiè, A Torbicki - Heart, 2001 - heart.bmj.com
WHO classification that is intended to group diseases with similar pathologic,
pathophysiologic, clinical, and therapeutic features. The second category—pulmonary …

Pulmonary arterial hypertension: challenges in translational research and a vision for change

G Sutendra, ED Michelakis - Science translational medicine, 2013 - science.org
Pulmonary arterial hypertension (PAH) is a vascular remodeling disease with a relentless
course toward heart failure and early death. Existing PAH therapies, all of which were …

A review of therapeutic agents for the management of pulmonary arterial hypertension

SS Hahn, M Makaryus, A Talwar… - Therapeutic …, 2017 - journals.sagepub.com
Pulmonary arterial hypertension (PAH) is an uncommon, progressive and life threatening
disease characterized by a proliferative vasculopathy of the small muscular pulmonary …

New insights on pulmonary arterial hypertension

N Galiè, A Manes, A Branzi - Revista Española de Cardiología (English …, 2004 - Elsevier
The 3rd World Symposium on Pulmonary Arterial Hypertension has been a forum for the
presentation and discussion of overviews on several aspects of this devastating disease …

Beyond the lungs: systemic manifestations of pulmonary arterial hypertension

NP Nickel, K Yuan, P Dorfmuller… - American Journal of …, 2020 - atsjournals.org
Pulmonary arterial hypertension (PAH) is a disease characterized by progressive loss and
remodeling of the pulmonary arteries, resulting in right heart failure and death. Until recently …