A critical review of in vitro research methodologies used to study mineralization in human dental pulp cell cultures

S Arora, PR Cooper, JT Ratnayake… - International …, 2022 - Wiley Online Library
Background The pulp contains a resident population of stem cells which can be stimulated
to differentiate in order to repair the tooth by generating a mineralized extracellular matrix …

Characterization of odontoblast-like cell phenotype and reparative dentin formation in vivo: a comprehensive literature review

D Tziafas - Journal of endodontics, 2019 - Elsevier
Introduction The primary aim was to explore the criteria used in characterization of
reparative cells and mineralized matrices formed after treatment of pulp exposures, and the …

Expression of mineralization markers in dental pulp cells

X Wei, J Ling, L Wu, L Liu, Y Xiao - Journal of endodontics, 2007 - Elsevier
There is an increasing interest in the utility of dental pulp stem cells (DPSCs) for dentin
regeneration. The mechanisms involved in DPSC differentiation remain poorly understood …

Dental pulp stem cells for bone tissue engineering: a review of the current literature and a look to the future

M Cristaldi, R Mauceri, L Tomasello, G Pizzo… - Regenerative …, 2018 - Taylor & Francis
The aim of this narrative review is to investigate the implication of mesenchymal stem cells
harvested from human dental pulp in in vivo bone tissue regeneration. We focused on …

[HTML][HTML] Dentin-like tissue formation and biomineralization by multicellular human pulp cell spheres in vitro

J Neunzehn, MT Weber, G Wittenburg, G Lauer… - Head & Face …, 2014 - Springer
Introduction Maintaining or regenerating a vital pulp is a preferable goal in current
endodontic research. In this study, human dental pulp cell aggregates (spheres) were …

Dentin extracellular matrix molecules implanted into exposed pulps generate reparative dentin: a novel strategy in regenerative dentistry

M Goldberg, N Six, C Chaussain… - Journal of dental …, 2009 - journals.sagepub.com
For years, dental surgeons have used calcium hydroxide as the 'gold standard'therapy for
direct pulp-capping. Depending on the degree of bacterial contamination, pulp inflammation …

Isolation, characterization and comparative differentiation of human dental pulp stem cells derived from permanent teeth by using two different methods

R Karamzadeh, MB Eslaminejad… - JoVE (Journal of …, 2012 - jove.com
Developing wisdom teeth are easy-accessible source of stem cells during the adulthood
which could be obtained by routine orthodontic treatments. Human pulp-derived stem cells …

Missing Concepts in De Novo Pulp Regeneration

GTJ Huang, F Garcia-Godoy - Journal of dental research, 2014 - journals.sagepub.com
Regenerative endodontics has gained much attention in the past decade because it offers
an alternative approach in treating endodontically involved teeth. Instead of filling the canal …

MEPE is downregulated as dental pulp stem cells differentiate

H Liu, W Li, S Shi, S Habelitz, C Gao… - Archives of Oral Biology, 2005 - Elsevier
Previous studies on dental pulp cell culture have described heterogenous mixtures of cells
that differentiate into odontoblasts and form mineralized dentin. OBJECTIVE:: The aim of this …

Stem cell‐based pulp tissue engineering: variables enrolled in translation from the bench to the bedside, a systematic review of literature

MCM Conde, LA Chisini, FF Demarco… - International …, 2016 - Wiley Online Library
Stem cell‐based therapy (SC‐BT) is emerging as an alternative for endodontic therapies.
The interaction between stem cells and scaffolds plays a crucial role in the generation of a …