Two siblings with 46, XY male pseudohermaphroditism were demonstrated to have the
phenotype characteristic of 5α-reductase deficiency, namely normal testes and male …

The 5α‐reductase activity that mediates the transformation of testosterone to
dihydrotestosterone in various anatomical sites of human beings, has been studied in …

Abstract The enzyme steroid 5 [alpha]-reductase converts testosterone to the more potent
androgen dihydrotestosterone. An inherited deficiency of the enzyme results in a deficiency …

In two siblings with male pseudohermaphroditism (ambiguous external genitalia, XY
karyotype) and apparently normal glucocorticoid function, plasma concentrations of 10 …

The in vitro metabolism of radioactive labeled testosterone and androstenedione by a
minced preparation of pubic skin from a patient with the complete testicular feminization …

We report here the results of the endocrine studies and the morphological findings of the
gonads in two male pseudohermaphrodite siblings with 5 alpha-reductase deficiency. Basal …

Abstract 17 beta-Hydroxysteroid dehydrogenase (17 beta HSD) deficiency is a rare cause of
male pseudohermaphroditism, but is a frequent disorder among a highly inbred Arab …

In order to document testicular 17β-reduction deficiency (17RD) and to search for additional
metabolic aberrations possibly associated with this disorder, the metabolism of 14C-labeled …

Testicular function was evaluated in forty‐one prepubertal patients with male
pseudohermaphroditism by determinating serum concentrations of progesterone, 17 …

I. Introduction B ETWEEN 1968 and 1973 a large body of evidence accumulated in our
laboratory and by others demonstrated that the conversion of testosterone to …