The dynamic physiological changes that occur in the maternal-placental-fetal unit during
pregnancy influence the pharmacokinetic processes of drug absorption, distribution and …

Any drug given to a pregnant woman must be considered as possibly harmful to the fetus,
since all drugs administered to the mother cross the placental membrane, although at …

Changes in maternal physiology occur normally during pregnancy and have the potential to
alter the absorption, distribution, and elimination of drugs used therapeutically in pregnant …

Significant changes in the physiological and biotransformation processes that govern
pharmacokinetics occur during pregnancy. Consequently, the disposition of many …

Pharmacokinetics is concerned with the description of drug absorption, distribution,
metabolism and excretion and with the time course of the pharmacological effects that …

The pharmacokinetics of many drugs are altered by pregnancy. Drug distribution and protein
binding are changed by pregnancy. While some drug metabolizing enzymes have an …

Pharmacologic interventions play a major role in obstetrical care throughout pregnancy,
labor and delivery and the postpartum. Traditionally, obstetrical providers have utilized …

Pharmacokinetics describes the handling of a drug by the body–how the drug is absorbed,
distributed and eliminated and how these processes determine plasma concentrations of the …

Physiologic changes in pregnancy induce profound alterations to the pharmacokinetic
properties of many medications. These changes affect distribution, absorption, metabolism …

Drugs ingested by a lactating mother would be expected to appear in human milk to some
extent and be ingested by a breast-feeding infant. Drugs pass from maternal plasma into …