Breastfeeding is the optimal form of infant feeding for the first months of an infant's life, and
the majority of healthy women initiate breastfeeding after the birth of their infant. However …

Publisher Summary This chapter discusses three major components that affect drug transfer
into human milk and the suckling infant, including maternal pharmacokinetics, mammary …

Breastfeeding has positive health consequences for both the breastfed infant and the
nursing mother. 1, 2 Although information on drug use during lactation is available through …

Knowledge of pharmacokinetics and the use of a mechanistic-based approach can improve
our ability to predict the effects of pregnancy for medications when data are limited. Despite …

The book discusses the mechanisms of drug transfer into human milk, summarizes current
knowledge of infant dose and safety for major drug groups, and provides a set of tools for …

The trend globally for mothers to breastfeed has highlighted the need for information on drug
transfer into breast milk and the extent to which the suckling neonate may be exposed and …

Many mothers are inappropriately advised to discontinue breastfeeding or avoid taking
essential medications because of fears of adverse effects on their infants. This cautious …

Most drugs appear in breast milk in very small and safe amounts. The obstetric care provider
evaluates drug transfer most commonly in the peripartum period, postpartum hospitalization; …

Background: Successful practice of clinical perinatal pharmacology requires a thorough
understanding of the pronounced physiological changes during lactation and how these …

There is continuing emphasis by many professionals and organizations on the importance of
breastfeeding as optimal infant nutrition. Pediatricians are frequently asked about the safety …