Thermally-triggered fabrication of cell sheets for tissue engineering and regenerative medicine

H Takahashi, T Okano - Advanced drug delivery reviews, 2019 - Elsevier
Cell transplantation is a promising approach for promoting tissue regeneration in the
treatment of damaged tissues or organs. Although cells have conventionally been delivered …

Reconstruction of functional tissues with cell sheet engineering

J Yang, M Yamato, T Shimizu, H Sekine, K Ohashi… - Biomaterials, 2007 - Elsevier
The field of tissue engineering has yielded several successes in early clinical trials of
regenerative medicine using living cells seeded into biodegradable scaffolds. In contrast to …

Cell delivery in regenerative medicine: the cell sheet engineering approach

J Yang, M Yamato, K Nishida, T Ohki, M Kanzaki… - Journal of Controlled …, 2006 - Elsevier
Recently, cell-based therapies have developed as a foundation for regenerative medicine.
General approaches for cell delivery have thus far involved the use of direct injection of …

Cell sheet engineering: recreating tissues without biodegradable scaffolds

J Yang, M Yamato, C Kohno, A Nishimoto, H Sekine… - Biomaterials, 2005 - Elsevier
While tissue engineering has long been thought to possess enormous potential,
conventional applications using biodegradable scaffolds have limited the field's progress …

Scaffold-free tissue engineering using cell sheet technology

Y Haraguchi, T Shimizu, M Yamato, T Okano - RSC advances, 2012 - pubs.rsc.org
Cell sheet technology is a tissue engineering methodology requiring no scaffolds. Confluent
cultured cells can be harvested as an intact cell sheet using a temperature-responsive …

Temperature-responsive cell culture surfaces for regenerative medicine with cell sheet engineering

M Yamato, Y Akiyama, J Kobayashi, J Yang… - Progress in Polymer …, 2007 - Elsevier
We have developed a novel strategy for regenerative medicine to recover tissue functions by
using temperature-responsive cell culture surfaces. To overcome the limits of conventional …

[HTML][HTML] Recent advances in cell sheet engineering: from fabrication to clinical translation

P Thummarati, W Laiwattanapaisal, R Nitta, M Fukuda… - Bioengineering, 2023 - mdpi.com
Cell sheet engineering, a scaffold-free tissue fabrication technique, has proven to be an
important breakthrough technology in regenerative medicine. Over the past two decades …

A surface‐tailoring method for rapid non‐thermosensitive cell‐sheet engineering via functional polymer coatings

J Baek, Y Cho, HJ Park, G Choi, JS Lee… - Advanced …, 2020 - Wiley Online Library
Cell sheet engineering, a technique utilizing a monolayer cell sheet, has recently emerged
as a promising technology for scaffold‐free tissue engineering. In contrast to conventional …

Cell sheet engineering for regenerative medicine: current challenges and strategies

T Owaki, T Shimizu, M Yamato… - Biotechnology journal, 2014 - Wiley Online Library
Substantial progress made in the areas of stem cell research and regenerative medicine has
provided a number of innovative methods to repair or regenerate defective tissues and …

Recent development of temperature-responsive surfaces and their application for cell sheet engineering

Z Tang, T Okano - Regenerative biomaterials, 2014 - academic.oup.com
Cell sheet engineering, which fabricates sheet-like tissues without biodegradable scaffolds,
has been proposed as a novel approach for tissue engineering. Cells have been cultured …