Objective: Accumulation of visceral fat is recognized as a predictor of obesity‐related
metabolic disturbances. Factors that are predominantly expressed in this depot could …

Low-grade inflammation is involved in endothelial dysfunction, atherosclerosis and
cardiovascular disease (CVD)[1]. The complement system is an ancient inducer of …

Background Complement factor C3 and C4 have been associated with atherosclerosis and
cardiovascular risk factors. This study explored whether plasma levels of C3 and C4 are risk …

Introduction Obesity is frequently characterized by chronic inflammation and insulin
resistance (IR). Obesity-associated inflammation is responsible for the complement system …

We studied whether serum complement C3 (C3) is an independent determinant of incident
cardiometabolic risk (coronary heart disease [CHD], metabolic syndrome [MetS], and type 2 …

C3 is the central component of the complement system and activation of C3 via any of the
three major activation pathways—the classical, the lectin and the alternative pathways …

Background It has been suggested that action of complement cascade [CC]-derived
anaphylatoxins/molecules may represent a missing link between obesity and metabolic …

In recent years, there has been a growing recognition of the role of inflammation in the
aetiology of atherothrombotic vascular disease. The associations of C-reactive protein and …

Eur J Clin Invest 2011; 41 (4): 372–379 Abstract Background Complement C3, a central
component of the innate immune system is increased in subjects with obesity and type 2 …

Adipose tissue inflammation has recently been linked to the pathogenesis of obesity and
insulin resistance. C1 complex comprising three distinct proteins, C1q, C1r, and C1s …