BACKGROUND: Complement C3 is an emerging risk factor for coronary heart disease
(CHD) and is particularly increased in the metabolic syndrome. A direct effect of smoking on …

Eur J Clin Invest 2012; 42 (5): 503–509 Abstract Background Circulating C3 levels are
elevated in obese patients, but how this factor is affected after weight loss through diet is a …

BACKGROUND: Serum C3 is an inflammatory predictor of myocardial infarction and a
covariate of fasting insulin and several endogenous risk factors. This study was performed to …

In the present study, we examined (i) whether C3 (complement C3) was an independent
marker of prevalent CHD (coronary heart disease), and (ii) which preferential associations …

This review summarizes available evidence on the role of serum complement component 3
(C3), produced by liver, adipocytes and activated macrophages at inflammation sites, and …

Aims To investigate whether serum complement C3 is related to the prevalence and
incidence of prediabetes in an adult population. Methods A cross‐sectional (n= 10 206) and …

Purpose This study explored whether complement factor 3 (C3) in plasma is associated with
incidence of diabetes in a population-based cohort. We also identified genetic variants …

Inflammation is an important mediator of obesity-related complications such as the metabolic
syndrome but its causes and mechanisms are unknown. As the complement system is a key …

Background Increased serum complement C3 has been related to body fat mass, metabolic
syndrome and chronic diseases. The purpose of this study was to evaluate the levels of C3 …

Complement C3 is a novel risk factor for cardiovascular disease (CVD), but the underlying
mechanism is currently unknown. We determined the associations of the anaphylatoxin C3a …