Relationships of complement components C3 and C4 and their genetics to cardiometabolic risk in healthy, non-Hispanic white adolescents

MM Copenhaver, CY Yu, D Zhou, RP Hoffman - Pediatric research, 2020 - nature.com
Background Complement promotes inflammatory and immune responses and may affect
cardiometabolic risk. This study was designed to investigate the effect of complement …

Correlations between serum lipids and complement components in adults without demonstrated atherosclerotic disease

A Muscari, C Bozzoli, GM Puddu, C Rovinetti… - Atherosclerosis, 1990 - Elsevier
The variability due to age and sex and the reciprocal relations of serum IgG, IgA, IgM, C3,
C4, total cholesterol (TC), HDL-cholesterol (HDL-C) and triglycerides (TG) were studied in …

Short term effect of atorvastatin and vitamin E on serum levels of C3, a sensitive marker of the risk of myocardial infarction in men

A Muscari, L Bastagli, G Poggiopollini… - … drugs and therapy, 2001 - Springer
C3 complement is produced in response to macrophage activation and is a reliable marker
of the risk of myocardial infarction in men. This study was designed to ascertain whether the …

[PDF][PDF] Complement activation in hypercholesterolemia

AL Pasqui, G Bova, L Puccetti, F Bruni… - NUTRITION …, 2000 - researchgate.net
Abstract Background and Aim: Inflammatory and lipid factors share an important role in
atherosclerosis. This study evaluates their relations in dyslipidemic subjects. Methods and …

[HTML][HTML] Inflammatory proteins are related to total and abdominal adiposity in a healthy adolescent population: the AVENA Study

J Wärnberg, E Nova, LA Moreno, J Romeo… - The American journal of …, 2006 - Elsevier
Background: In adults, obesity is characterized by a state of chronic low-grade inflammation
accompanied by moderately high concentrations of acute phase inflammatory proteins …

Adipokines and the immune system: an adipocentric view

R MacLaren, W Cui, K Cianflone - Current topics in complement II, 2008 - Springer
There is increasing evidence of close interactions between the adipose and the immune
systems. Adipocytes secrete multiple factors, including adipokines such as leptin and …

CD11c expression in adipose tissue and blood and its role in diet-induced obesity

H Wu, XD Perrard, Q Wang, JL Perrard… - … , and vascular biology, 2010 - Am Heart Assoc
Objective—To examine CD11c, a β2-integrin, on adipose tissue (AT) leukocytes and blood
monocytes and its role in diet-induced obesity. Methods and Results—High-fat diet–induced …

[HTML][HTML] Complement C3 and C4, but not their regulators or activated products, are associated with incident metabolic syndrome: the CODAM study

Y Xin, E Hertle, CJH van der Kallen, CG Schalkwijk… - Endocrine, 2018 - Springer
Purpose We investigated the associations of components of the alternative (C3, C3a, Bb,
factor D [FD], factor H [FH], properdin) and the classical complement pathway (C4, C1q, C1 …

The complement anaphylatoxin C5a receptor contributes to obese adipose tissue inflammation and insulin resistance

J Phieler, KJ Chung, A Chatzigeorgiou… - The Journal of …, 2013 - journals.aai.org
Obese adipose tissue (AT) inflammation contributes critically to development of insulin
resistance. The complement anaphylatoxin C5a receptor (C5aR) has been implicated in …

The metabolic syndrome in relation to complement component 3 and postprandial lipemia in patients from an outpatient lipid clinic and healthy volunteers

AJ Van Oostrom, A Alipour, TWM Plokker… - Atherosclerosis, 2007 - Elsevier
We investigated the relationship between complement component 3 (C3), fasting and
postprandial lipemia and the metabolic syndrome (MetabS). Herefore fasting and …