OBJECTIVE: An elevated C3 concentration has been reported in people with obesity, type 2
diabetes, hypertension, and dyslipidemia, and has been proposed to play a role in the …

Background Obesity is considered as a systemic chronic low grade inflammation
characterized by increased serum pro-inflammatory proteins and accumulation of …

Familial hypercholesterolemia (FH) is increasingly associated with inflammation, a
phenotype that persists despite treatment with lipid lowering therapies. The alternative C3 …

Objectives It is well-known that the complement system plays an essential role in host
immunity. Observational studies have indicated that complement system-related molecules …

Adipose tissue is a major source of adpisin/factor D of the alternative pathway of
complement. Adipose tissue also expresses the two other complement components which …

Objective—We have previously shown an increased expression of complement 3 (C3) in the
perivascular adipose tissue (PVAT) in the deoxycorticosterone acetate (DOCA)–salt …

There is a temporal window from the time diabetes is diagnosed to the appearance of overt
kidney disease during which time the disease progresses quietly without detection …

Background and Purpose—Complement components are emerging risk factors for
cardiovascular disease. In this study, we examined the relation among C3, C-reactive …

Soluble CD14 (sCD14), detectable at high concentrations constitutively present in the
circulation, plays a key role in the neutralization of lipopolysaccharide, one of the most …

Objective: The purpose of this study was to determine the relationships between adipocyte
hormones acylation stimulating protein (ASP), adiponectin, complement C3 (C3)(ASP …