C5aR and C3aR antagonists each inhibit diet‐induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling
Mammalian survival depends on metabolizing nutrients, storing energy, and combating
infection. Complement activation in blood triggers energy‐depleting immune responses to …
infection. Complement activation in blood triggers energy‐depleting immune responses to …
A new effector of lipid metabolism: complement factor properdin
D Gauvreau, C Roy, FQ Tom, HL Lu, P Miegueu… - Molecular …, 2012 - Elsevier
BACKGROUND: The complement system is well known for its role in innate immunity via the
classical, the alternative and the lectin pathways, although recent investigations suggest …
classical, the alternative and the lectin pathways, although recent investigations suggest …
Postprandial inflammation and endothelial dysfuction
A Alipour, JWF Elte, HCT Van Zaanen… - Biochemical Society …, 2007 - portlandpress.com
Postprandial hyperlipidaemia is a common metabolic disturbance in atherosclerosis. During
the postprandial phase, chylomicrons and their remnants can penetrate the intact …
the postprandial phase, chylomicrons and their remnants can penetrate the intact …
Genetic contribution to C-reactive protein levels in severe obesity
G Faucher, F Guénard, L Bouchard, V Garneau… - Molecular Genetics and …, 2012 - Elsevier
Obese individuals are characterized by a chronic, low-grade inflammatory state. Increased
levels of C-reactive protein (CRP), a marker of inflammation, have been observed in …
levels of C-reactive protein (CRP), a marker of inflammation, have been observed in …
High levels of saturated very long-chain fatty acid (hexacosanoic acid; C26: 0) in whole blood are associated with metabolic syndrome in Japanese men
A Kume, T Miyazaki, Y Kitamura, K Oshida… - diabetes research and …, 2008 - Elsevier
OBJECTIVE: Hexacosanoic acid (C26: 0) is a saturated very long-chain fatty acid and high
levels of C26: 0 in red blood cells are reported to be closely related with risk factors of …
levels of C26: 0 in red blood cells are reported to be closely related with risk factors of …
Specific macrophage subsets accumulate in human subcutaneous and omental fat depots during obesity
A Girón‐Ulloa, E González‐Domínguez… - … and Cell Biology, 2020 - Wiley Online Library
Obesity is a chronic inflammatory disease associated with adipose tissue macrophage
(ATM) activation. ATMs from lean mice contribute to tissue homeostasis by their M2‐oriented …
(ATM) activation. ATMs from lean mice contribute to tissue homeostasis by their M2‐oriented …
Relations of visceral and abdominal subcutaneous adipose tissue, body mass index, and waist circumference to serum concentrations of parameters of chronic …
I Schlecht, B Fischer, G Behrens, MF Leitzmann - Obesity facts, 2016 - karger.com
Background: Different measures of body fat composition may vary in their relations to
parameters of chronic inflammation. Methods: We assessed the relations of visceral (VAT) …
parameters of chronic inflammation. Methods: We assessed the relations of visceral (VAT) …
Lean body mass and creatine kinase are associated with reduced inflammation in obesity
SI Bekkelund, R Jorde - European journal of clinical …, 2017 - Wiley Online Library
Background Obesity is associated with inflammation, but the role of lean mass and creatine
kinase (CK) on the inflammatory process is less known. We investigated the associations …
kinase (CK) on the inflammatory process is less known. We investigated the associations …
[PDF][PDF] The anti-inflammatory and bioregulatory effects of habitual exercise in high-fat diet-induced obesity involve crown-like structures and MCP-1 in white adipose …
I Gálvez, M Dolores Hinchado… - Exercise Immunology …, 2023 - eir-isei.de
Macrophage accumulation in the adipose tissue and changes in their inflammatory
phenotype is a hallmark of obesity-induced inflammation, notably forming inflammatory …
phenotype is a hallmark of obesity-induced inflammation, notably forming inflammatory …
Inflammation may modulate IL-6 and C-reactive protein gene expression in the adipose tissue: the role of IL-6 cell membrane receptor
Only few studies have been addressed to the presence and regulation of C-reactive protein
(CRP) gene expression in different districts of adipose tissue, and no study has investigated …
(CRP) gene expression in different districts of adipose tissue, and no study has investigated …