[HTML][HTML] Bioengineered uterine tissue supports pregnancy in a rat model

M Hellström, JM Moreno-Moya, S Bandstein, E Bom… - Fertility and sterility, 2016 - Elsevier
Objective To create a bioengineered uterine patch for uterine repair of a partially defect
uterus. Design Three different decellularized uterine scaffolds were recellularized in vitro …

Therapeutic effect of human amniotic epithelial cells in rat models of intrauterine adhesions

X Bai, J Liu, W Yuan, Y Liu, W Li, S Cao… - Cell …, 2020 - journals.sagepub.com
As a refractory fibrosis disease, intrauterine adhesions (IUAs) is defined as fibrosis of the
physiological endometrium. Although hysteroscopic adhesiolysis is widely recommended as …

Endometrial stem cells repair injured endometrium and induce angiogenesis via AKT and ERK pathways

Y Zhang, X Lin, Y Dai, X Hu, H Zhu, Y Jiang… - …, 2016 - rep.bioscientifica.com
Intrauterine adhesions are common acquired endometrial syndromes secondary to
endometrial injury, with limited effective therapies. Recently, several studies have reported …

Regeneration of uterine horns in rats by collagen scaffolds loaded with collagen-binding human basic fibroblast growth factor

H Sun, N Lin, X Hou, J Wang, B Zhou, P Xu, Z Xiao… - Biomaterials, 2011 - Elsevier
Severe damages of uterine endometrium which prevent embryos from implantation and
placentation finally often result in infertility or pregnant complications. There is lack of …

[HTML][HTML] In situ delivery of apoptotic bodies derived from mesenchymal stem cells via a hyaluronic acid hydrogel: a therapy for intrauterine adhesions

L Xin, C Wei, X Tong, Y Dai, D Huang, J Chen, L Ma… - Bioactive materials, 2022 - Elsevier
Stem cell-based and stem cell-derived exosome-based therapies have shown promising
potential for endometrial regeneration and the clinical treatment of intrauterine adhesions …

3D Bioprinting a human iPSC-derived MSC-loaded scaffold for repair of the uterine endometrium

W Ji, B Hou, W Lin, L Wang, W Zheng, W Li, J Zheng… - Acta Biomaterialia, 2020 - Elsevier
Common events in the clinic, such as uterine curettage or inflammation, may lead to
irreversible endometrial damage, often resulting in infertility in women of childbearing age …

Placental-derived biomaterials and their application to wound healing: a review

NM Protzman, Y Mao, D Long, R Sivalenka… - Bioengineering, 2023 - mdpi.com
Chronic wounds are associated with considerable patient morbidity and present a significant
economic burden to the healthcare system. Often, chronic wounds are in a state of persistent …

Management of intrauterine adhesions: a novel intrauterine device

CH Tu, XL Yang, XY Qin, LP Cai, P Zhang - Medical Hypotheses, 2013 - Elsevier
Intrauterine adhesions (IUAs) are a rare but significant cause of menstrual disturbance and
infertility. Most cases are caused by uterine instrumentation. Several methods have been …

Making more womb: clinical perspectives supporting the development and utilization of mesenchymal stem cell therapy for endometrial regeneration and infertility

M Strug, L Aghajanova - Journal of Personalized Medicine, 2021 - mdpi.com
The uterus is a homeostatic organ, unwavering in the setting of monthly endometrial
turnover, placental invasion, and parturition. In response to ovarian steroid hormones, the …

Homogenous subpopulation of human mesenchymal stem cells and their extracellular vesicles restore function of endometrium in an experimental rat model of …

N Mansouri-Kivaj, A Nazari, F Esfandiari… - Stem Cell Research & …, 2023 - Springer
Background Asherman syndrome (AS), or intrauterine adhesions, is a main cause of
infertility in reproductive age women after endometrial injury. Mesenchymal stem cells …