Medial septal and nucleus basalis magnocellularis lesions produce order memory deficits in rats which mimic symptomatology of Alzheimer's disease
RP Kesner, KA Crutcher, MO Measom - Neurobiology of Aging, 1986 - Elsevier
Rats with electrolytic lesions of the medial septum or ibotenic acid lesions of the nucleus
basalis magnocellularis (NBM) were tested in an order memory task for an 8-item list of …
basalis magnocellularis (NBM) were tested in an order memory task for an 8-item list of …
Damage to hippocampus and hippocampal connections: effects on DRL and spontaneous alternation.
CT Johnson, DS Olton, FH Gage… - journal of Comparative …, 1977 - psycnet.apa.org
A total of 162 male Sprague-Dawley albino rats were tested both pre-and postoperatively
either on a DRL 20-sec schedule (Exp I) or for spontaneous alternation (Exp II). Selective …
either on a DRL 20-sec schedule (Exp I) or for spontaneous alternation (Exp II). Selective …
Effects of repeated disorientation on the acquisition of spatial tasks in rats: dissociation between the appetitive radial arm maze and aversive water maze.
PA Dudchenko, JP Goodridge, DA Seiterle… - Journal of …, 1997 - psycnet.apa.org
This study examined the effects of disorientation on the acquisition of different spatial
reference memory tasks. In an appetitively motivated radial arm maze task in which 1 arm …
reference memory tasks. In an appetitively motivated radial arm maze task in which 1 arm …
Hippocampal resections impair associative learning and recognition memory in the monkey
H Mahut, S Zola-Morgan, M Moss - Journal of Neuroscience, 1982 - Soc Neuroscience
Damage to the hippocampus has been implicated in the permanent loss of memory in
patients with medial temporal lobe resections. In two previous studies, it was established …
patients with medial temporal lobe resections. In two previous studies, it was established …
Assessment of spatial memory using the radial arm maze and Morris water maze
GL Wenk - Current protocols in neuroscience, 2004 - Wiley Online Library
Behavioral tasks must be evaluated in terms of the cognitive functions they require in order
to be performed. All of the tasks described in this chapter can be used with each of four …
to be performed. All of the tasks described in this chapter can be used with each of four …
Spontaneous recognition of object configurations in rats: effects of fornix lesions
A Ennaceur, JP Aggleton - Experimental brain research, 1994 - Springer
The effects of fornix lesions were examined in an object recognition memory test based on
spontaneous exploration. In the standard condition an object (A) was presented in the …
spontaneous exploration. In the standard condition an object (A) was presented in the …
A comparison of the effects of medial prefrontal, cingulate cortex, and cingulum bundle lesions on tests of spatial memory: evidence of a double dissociation between …
JP Aggleton, N Neave, S Nagle… - Journal of …, 1995 - Soc Neuroscience
Rats were trained on an automated delayed nonmatching-to-position (DNMP) task. They
then received cytotoxic lesions in either the medial prefrontal cortex (n= 13) or the cingulate …
then received cytotoxic lesions in either the medial prefrontal cortex (n= 13) or the cingulate …
Effects of dorsal and ventral hippocampal lesions on spontaneous alternation, learned alternation and probability learning in rats
R Stevens, A Cowey - Brain research, 1973 - Elsevier
In a series of 3 experiments it was shown that lesions restricted to the dorsal or ventral
portions of the hippocampus in rats produced different effects on behaviour. Animals with …
portions of the hippocampus in rats produced different effects on behaviour. Animals with …
On the trail of the hippocampal engram
J O'keefe, DH Conway - Physiological Psychology, 1980 - Springer
Recent ideas about hippocampal function in animals suggest that it may be involved in
memory. A new test for rat memory is described (the despatch task). It has several properties …
memory. A new test for rat memory is described (the despatch task). It has several properties …
Hippocampal and prefrontal cortex contributions to learning and memory: analysis of lesion and aging effects on maze learning in rats.
G Winocur, M Moscovitch - Behavioral neuroscience, 1990 - psycnet.apa.org
Young adult rats with bilateral lesions to the hippocampus or prefrontal cortex, young
operated controls, and normal old rats were tested on two complex mazes in the Hebb …
operated controls, and normal old rats were tested on two complex mazes in the Hebb …