Parkinson's disease (PD) is a progressive neurodegenerative disease, leading to tremor,
rigidity, bradykinesia, and gait impairment. Salidroside has been reported to exhibit …

SIRT3 is a member of Sirtuins family, which belongs to NAD+ dependent class III histone
deacetylases. Emerging evidence suggests that SIRT3 plays a pivotal role in regulating …

Aims: Parkinson's disease (PD) heavily affects humans and little is known about its cause
and pathogenesis. Sirtuin 3 (Sirt3) plays a key role in regulating mitochondrial dysfunction …

Silent information regulator 1 (SIRT1), an NAD+‐dependent deacetylase, is involved in the
regulation of gene transcription, energy metabolism, and cellular aging and has become an …

Antimony (Sb) has been reported to lead to pulmonary damage, but the underlying
mechanism remains unclear. Accumulating evidence indicates that silent mating type …

Abstract Sirtuin1 (SIRT1) has protective effects in some neurodegenerative disease models,
but it is not clear whether SIRT1 play the same role on inflammation-mediated Parkinson's …

Abstract Sirtuin 2 (SIRT2) is a member of the sirtuin family. Previous studies have suggested
that SIRT2 mediates the cell death in models of Parkinson's disease and Huntington's …

Increasing evidence indicates that sirtuin 1 (SIRT1) is implicated in a wide range of cellular
functions, such as oxidative stress, inflammation and apoptosis. The aim of this study was to …

Silent information regulator (SIRT) has distinctive enzymatic activities and physiological
functions to control cell-cycle progression, gene expression, and DNA stability by targeting …

Cerebral ischemia (CI) is a severe cause of neurological dysfunction and mortality. Sirtuin-1
(Silent information regulator family protein 1, SIRT1), an oxidized nicotinamide adenine …