The classification of acute myeloid leukemia (AML) recognizes a subgroup of diseases with
recurring genetic abnormalities. Translocation (15; 17) is the marker of acute promyelocitic …

Cytogenetic abnormalities play an important role in diagnosis, classification and prognosis
in acute myeloid leukemia (AML). Nevertheless, several chromosome abnormalities have …

Chromosomal rearrangements involving the MLL gene (approved symbol: KMT2A) at 11q23
are associated with different types of hematological malignancies, with more than 70 fusion …

Chromosome 21 and in particular band 21q22, the site of AML1 (RUNX1, CBFA2) gene, is
among the most frequent targets of chromosomal translocations in leukemia observed in …

Acute myeloid leukemia (AML) is characterized by chromosomal abnormalities affecting
both prognosis and course of treatment. While most AML patients have well described …

A case of acute monocytic leukemia (AMoL) with t (5; 11)(q31; q23) and a case of acute
myelomonocytic leukemia (AMMoL) with t (5; 11)(q35; q13. 1) are reported. The …

The translocation (8; 21)(q22; q22) is a frequent karyotypic abnormality in acute
myelogenous leukemia (AML). Most cases of AML with t (8; 21) show an M2 phenotype …

A new variant translocation,(8; 20)(q22; q13) in a patient with acute myelocytic leukemia
(AML) M2 is reported. As far as we know, this is the second case of the t (8; 20) in de novo …

Acute myeloid leukemia (AML) with t (8; 21)(q22; q22) is well characterized by its unique
morphology of AML-M2 subtype and favorable prognosis [1]. This recurrent translocation is …

We reviewed the morphology of 110 acute myeloid leukemias (AML) with recurrent
cytogenetic/molecular translocations. The t (8; 21) cases had some pseudolymphoid blasts …