Because an increasing number of chromosomal aberrations have been detected in the
patients with acute leukemia, cytogenetic findings have become more valuable in …

Abstract The translocation (8; 21)(q22; q22) is associated with acute myeloblastic leukemia
(AML) with M2 subtype. The accurate detection of this chromosomal rearrangement is vital …

We report a patient with acute myeloid leukemia (AML) and t (3; 21; 8)(q21; q22; q22). This
translocation has not been previously described in de novo or relapsed AML. The patient is …

The reciprocal translocation between chromosomes 8 and 21 with breakpoints in 8q22 and
21q22 was first reported by Rowley, in 1973, 1 in a subgroup of patients with acute myeloid …

The cellular and molecular genetic aberrations of hematopoietic and lymphoid tissues are
increasingly important in leukemia classification and are prognostically significant. Although …

Abstract The translocation (8; 21)(q22; q22) is commonly associated with acute myeloid
leukemia (AML) M2 according to the French‐American‐British (FAB) classification. We …

We present a novel, rare but recurrent variant three way translocation of t (8; 21), t (8; 16;
21)(q22; q24; q22), as a primary cytogenetic abnormality, resulting in AML1/ETO fusion …

Objective To investigate the clinical and laboratory features of acute myeloid leukemia
(AML) with t (11; 12)(p15; q13) translocation. Methods Two cases of AML with t (11; 12)(p15; …

Abstract The t (8; 21)(q22; q22) is the most common translocation in acute myeloid leukemia
(AML). We describe the clinicopathologic and cytogenetic profile of 117 patients with t (8; 21) …

Cytogenetic abnormalities occur in approximately 60% of newly diagnosed patients with
acute myeloid leukaemia (AML) and are useful in the risk stratification of AML. Translocation …