Variant forms of the classic translocation t (8; 21) are uncommon and account approximately
3% of all t (8; 21)(q22; q22) in acute myeloid leukemia (AML) patients. These forms involve …

Abstract 11q23 translocations (t (11q23)) are recurring cytogenetic abnormalities in both
acute myeloid leukemia (AML) and acute lymphoblastic leukemia, involving the same gene …

The t (8; 21)(q22; q22) translocation involving RUNX1 at 21q22 and RUNX1T1 at 8q22 is
observed in 10% of cases of acute myeloid leukemia (AML) M2 subtype. 1 This translocation …

Acute myeloid leukemia (AML) with t (8; 21)(q22; q22) shows unique morphologic,
molecular, cytogenetic, and clinical features in patients with acute leukemia. It is closely …

The complex variants of t (8; 21) involving chromosomes 8 and 21 as well as a variable
chromosome account for 1.1∼ 5% of acute myeloid leukemia (AML) patients. This paper …

Acute myeloid leukemia (AML) is the most common acute leukemia in adults, with incidence
approaching 13,000 cases in the United States in 2008. It is diagnosed based on the …

A 59-year-old female suffering from malignant lymphoma developed therapy-related acute
myeloblastic leukemia (t-AML) after chemotherapy consisting of treatment with DNA …

Acute promyelocytic leukemia (APL) is a biologically and clinically distinct subtype of acute
myeloid leukemia (AML). APL is classified as AML-M3 in the French-American-British (FAB) …

A 35-year-old female patient was diagnosed with acute myeloid leukemia with multiple
genetic aberrations [48 XX, del (3)(q21),+ 6, t (11; 15)(q23; q15),+ 21] including an …

Introduction The transformation of acute myeloid leukemia with translocation (16; 16)(p13;
q22) from AML M2 to acute monocytic leukemia (AML M5) during therapy is a rare clinical …