T4 originates exclusively from the thyroid gland. In general, serum T4 levels decrease during
ESS (also referred to as non-thyroidal illness-NTI). This could potentially be explained by …

Abnormalities of thyroid hormone concentrations are seen commonly in a wide variety of
nonthyroidal illnesses, resulting in low triiodothyronine, total thyroxine, and thyroid …

Nonthyroidal illness (NTI) is associated with complex changes in thyroid function tests and
thyroid regulation known as the euthyroid sick syndrome (ESS)(1). The most common …

Thyroid hormone abnormalities are common in critically ill patients. For over three decades,
a mild form of these abnormalities has been described in patients with several diseases …

G ENERALLY, the purpose of assessing thyroid function in a given patient is to determine
his metabolic status. In patients with systemic nonthyroidal illness, as well as in those …

The mechanisms behind the changes in serum triiodothyronine (T (3)), thyroxine (T (4)) and
TSH that occur in the non-thyroidal illness syndrome (NTIS) are becoming clearer. Induction …

Multiple alterations in the serum concentration of the iodothyronines have been recognized
in patients with systemic non-thyroidal illnesses (NTI). Most prominent are the low serum 3 …

ABNORMALITIES IN THYROID HORMONE HOMEOSTASIS occur in a variety of
nonthyroidal illnesses. A decreased level of serum total triiodothyronine ([T. sub. 3]) is the …

In this review, we discuss the characteristics, pathophysiology, and therapeutic implications
of the euthyroid sick syndrome. Multiple mechanisms have been identified to contribute to …

The term Euthyroid Sick Syndrome (ESS) has been used for over 30 years to describe a
pattern of thyroid hormone alterations during non-thyroidal illness [1]. The degree of thyroid …