Effect of medial prefrontal cortex injections of SCH 23390 on intravenous cocaine self-administration under both a fixed and progressive ratio schedule of …
A McGregor, DCS Roberts - Behavioural brain research, 1995 - Elsevier
Rats were trained to self-administer cocaine (1.5 mg/kg iv) under either a fixed ratio (FR) or
progressive ratio (PR) schedule of reinforcement. Following acquisition, bilateral …
progressive ratio (PR) schedule of reinforcement. Following acquisition, bilateral …
Effect of 6-hydroxydopamine lesions of the medial prefrontal cortex on intravenous cocaine self-administration under a progressive ratio schedule of reinforcement
A McGregor, G Baker, DCS Roberts - Pharmacology Biochemistry and …, 1996 - Elsevier
Rats were trained to self-administer intravenous cocaine under a progressive ratio (PR)
schedule of reinforcement. Under this schedule, an increasing number of lever responses …
schedule of reinforcement. Under this schedule, an increasing number of lever responses …
Dopaminergic antagonism within the nucleus accumbens or the amygdala produces differential effects on intravenous cocaine self-administration under fixed and …
A McGregor, DCS Roberts - Brain research, 1993 - Elsevier
Bilateral intracerebral injections of the D1 receptor antagonist, SCH 23390, were
administered into the nucleus accumbens (NACC) or amygdala (AMY) immediately prior to …
administered into the nucleus accumbens (NACC) or amygdala (AMY) immediately prior to …
Effects of selective D1 and D2 dopamine antagonists on cocaine self-administration in the rat
CB Hubner, J Edward Moreton - Psychopharmacology, 1991 - Springer
The effect of the selective D1 antagonist, SCH 23390, and the selective D2 antagonist,
spiperone, was investigated in rats trained to self-administer intravenous cocaine on a fixed …
spiperone, was investigated in rats trained to self-administer intravenous cocaine on a fixed …
Targeting the dopamine D3 receptor cannot influence continuous reinforcement cocaine self-administration in rats
K Gál, I Gyertyán - Brain research bulletin, 2003 - Elsevier
Recent studies point out the important role of dopamine D3 receptors in drug addiction.
Therefore, D3 receptor ligands have been proposed as candidate medications for the …
Therefore, D3 receptor ligands have been proposed as candidate medications for the …
Selective dopamine D3 receptor antagonism by SB‐277011A attenuates cocaine reinforcement as assessed by progressive‐ratio and variable‐cost–variable‐payoff …
ZX Xi, JG Gilbert, AC Pak, CR Ashby Jr… - European Journal of …, 2005 - Wiley Online Library
In rats, acute administration of SB‐277011A, a highly selective dopamine (DA) D3 receptor
antagonist, blocks cocaine‐enhanced brain stimulation reward, cocaine‐seeking behaviour …
antagonist, blocks cocaine‐enhanced brain stimulation reward, cocaine‐seeking behaviour …
Pretreatment with the dopamine agonist 7-OH-DPAT shifts the cocaine self-administration dose-effect function to the left under different schedules in the rat
This study tested the hypothesis that administration of the dopamine agonist 7-hydroxy-N, N-
di-n-propyl-2-aminotetralin (7-OH-DPAT) shifts the cocaine self-administration dose-effect …
di-n-propyl-2-aminotetralin (7-OH-DPAT) shifts the cocaine self-administration dose-effect …
D1-like and D2 dopamine receptor antagonists administered into the shell subregion of the rat nucleus accumbens decrease cocaine, but not food, reinforcement
Cocaine self-administration experiments were designed to assess the respective roles of D1-
like and D2-like dopamine receptors in the ventral forebrain in cocaine reinforcement. D1 …
like and D2-like dopamine receptors in the ventral forebrain in cocaine reinforcement. D1 …
Effects of dopamine D1-like and D2-likeagonists in rats that self-administer cocaine
The reinforcing effects of D1-like and D2-likeagonists, and their capacity to modify cocaine
self-administration, were compared in rats with extensive cocaine self-administration …
self-administration, were compared in rats with extensive cocaine self-administration …
The dopamine D-1 receptor antagonist SCH 23390 injected into the dorsolateral bed nucleus of the stria terminalis decreased cocaine reinforcement in the rat
MP Epping-Jordan, A Markou, GF Koob - Brain research, 1998 - Elsevier
The effects of bilateral intracranial injections of the D-1 dopamine receptor antagonist SCH
23390 HCl (0, 0.8, 1.6, 3.2, and 6.4 μg total bilateral dose) administered into the dorsolateral …
23390 HCl (0, 0.8, 1.6, 3.2, and 6.4 μg total bilateral dose) administered into the dorsolateral …