DNA demethylation in Arabidopsis (Arabidopsis thaliana) is mediated by DNA glycosylases
of the DEMETER family. Three DEMETER-LIKE (DML) proteins, REPRESSOR OF …

De novo DNA methylation through the RNA-directed DNA methylation (RdDM) pathway and
active DNA demethylation play important roles in controlling genome-wide DNA methylation …

ABSTRACT DNA demethylases function in conjunction with DNA methyltransferases to
modulate genomic DNA methylation levels in plants. The Arabidopsis genome contains four …

Gene silencing by DNA methylation is well documented and known to be essential for
various biological phenomena in many organisms. In contrast, the processes that convert …

Cytosine DNA methylation is a stable epigenetic mark for maintenance of gene silencing
across cellular divisions, but it is a reversible modification. Genetic and biochemical studies …

DNA methylation is a conserved and important epigenetic mark in both mammals and
plants. DNA methylation can be dynamically established, maintained, and removed through …

Abstract The Arabidopsis ROS1/DEMETER family of 5-methylcytosine (5mC) DNA
glycosylases are the first genetically characterized DNA demethylases in eukaryotes …

Cytosine methylation is an epigenetic mark that promotes gene silencing and plays
important roles in development and genome defense against transposons. Methylation …

Cytosine DNA methylation is considered to be a stable epigenetic mark, but active
demethylation has been observed in both plants and animals. In Arabidopsis thaliana, DNA …

Active DNA demethylation is critical for altering DNA methylation patterns and regulating
gene expression. The 5‐methylcytosine DNA glycosylase/lyase ROS1 initiates a base …