Motor learning abilities on the rotorod and motor skills (muscular strength, motor
coordination, static and dynamic equilibrium) were investigated in three-, nine-, 15-and 21 …

Lurcher mutant mice represent a model of olivocerebellar degeneration. Due to loss of
Purkinje cells, they suffer from functional cerebellar decortication resulting in ataxia and …

The development of motor learning and topical motor skills has been studied during the first
month of life in neurodeficient Lurcher mutant mice derived from C3H strain. The …

Lurcher mutant mice, characterized by degeneration of the olivo-cerebellar system, were
evaluated in two tests of motor coordination: the inclined screen test and the tilted platform …

Adult heterozygous Lurcher mice show a degeneration of almost all Purkinje cells and 90%
of the granular cells of the cerebellum, resulting in ataxia or general deficits in motor …

Three-to 6-month-old lurcher mutant mice (+/lc), which exhibit a massive loss of neurons in
the cerebellar cortex and in the inferior olivary nucleus but whose deep cerebellar nuclei are …

Abstract Lurcher mutant mice (+/Lc) exhibit a massive loss of neurons in the cerebellar
cortex and the inferior olivary nucleus, while deep cerebellar nuclei are essentially intact. To …

Lurcher mutant mice lose cerebellar granule cells and Purkinje cells. The mutants were
compared to normal mice in a beam-walking task. Normal mice were placed on a slippery …

Lurcher mutant mice, characterized by degeneration of cerebellar granule and Purkinje
cells, were compared to normal littermate controls in a rotorod test, consisting of a wheel …

Lurcher mutant mice are characterized by massive degeneration of cerebellar Purkinje cells
and granule cells and by deficits in motor coordination. Regional brain variations of …