TAB3 promotes human esophageal squamous cell carcinoma proliferation and invasion via the NF‑κB pathway

J Zhao, L Gai, Y Gao, W Xia, D Shen… - Oncology …, 2018 - spandidos-publications.com
Esophageal squamous cell carcinoma (ESCC) has become one of the most common
causes of cancer‑associated mortality worldwide. Transforming growth factor‑activated …

TAB3 overexpression promotes cell proliferation in non-small cell lung cancer and mediates chemoresistance to CDDP in A549 cells via the NF-κB pathway

J Chen, J Gu, J Feng, Y Liu, Q Xue, T Ni, Z Wang, L Jia… - Tumor Biology, 2016 - Springer
Transforming growth factor-activated kinase 1 (TAK1)-binding protein 3 (TAB3) is essential
for the activation of the nuclear factor kappa B (NF-κB) pathway and has important roles in …

[HTML][HTML] TAB2 Promotes the Biological Functions of Head and Neck Squamous Cell Carcinoma Cells via EMT and PI3K Pathway

H Liu, H Zhang, H Fan, S Tang, J Weng - Disease Markers, 2022 - hindawi.com
Background. Transforming growth factor β 1-activated kinase 1 binding protein 2 (TAB2)
mediates a variety of biological processes through activated nuclear factor κ-light-chain …

Loss of TAB3 expression by shRNA exhibits suppressive bioactivity and increased chemical sensitivity of ovarian cancer cell lines via the NF‐κB pathway

Y Chen, X Wang, C Duan, J Chen, M Su, Y Jin… - Cell …, 2016 - Wiley Online Library
Ovarian cancer is a leading cause of death among gynaecologic malignancies. Despite
many years of research, it still remains sparing in reliable diagnostic markers and methods …

TAB182 aggravates progression of esophageal squamous cell carcinoma by enhancing β-catenin nuclear translocation through FHL2 dependent manner

A Gao, Z Su, Z Shang, C He, D Miao, X Li, S Zou… - Cell Death & …, 2022 - nature.com
Abstract TAB182 (also named TNKS1BP1), a binding protein of tankyrase 1, has been found
to participate in DNA repair. Our previous study has revealed the involvement of TAB182 in …

Positive transforming growth factor-β activated kinase-1 expression has an unfavorable impact on survival in T3N1-3M0 esophageal squamous cell carcinomas

J Wen, Y Hu, KJ Luo, H Yang, SS Zhang… - The Annals of thoracic …, 2013 - Elsevier
BACKGROUND: Transforming growth factor-β activated kinase-1 (TAK1) is a
serine/threonine kinase in the mitogen-activated protein kinase kinase family. Previous …

The expression and clinical significance of TAK1 in esophageal cancer

F Qiao, Q Tong - The Journal of Practical Medicine, 2014 - pesquisa.bvsalud.org
Objective To examine the expression of transforming growth factor β (TGF-β) activated
kinase 1 (TAK1) in esophageal organization and the impact of TAK1 expression on …

[HTML][HTML] TAB3 upregulates Survivin expression to promote colorectal cancer invasion and metastasis by binding to the TAK1-TRAF6 complex

C Luo, R Yuan, L Chen, W Zhou, W Shen, Y Qiu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Transforming growth factor-β-activated kinase 1 (TAK1)-binding protein 3 (TAB3) is involved
in cancer proliferation and metastasis, but its role in colorectal cancer remains unclear. In …

[HTML][HTML] Expression of TAK1/TAB1 expression in non-small cell lung carcinoma and adjacent normal tissues and their clinical significance

J Zhu, Q Li, JT He, GY Liu - International Journal of Clinical and …, 2015 - ncbi.nlm.nih.gov
The purpose of this study was to investigate the expression of transforming growth factor
beta-activated kinase 1 (TAK1) and its activation ligand, TAK1-binding protein 1 (TAB1), in …

Transforming growth factor-β activated kinase 1 (Tak1) is activated in hepatocellular carcinoma, mediates tumor progression, and predicts unfavorable outcome

DA Ridder, LL Urbansky, HR Witzel, M Schindeldecker… - Cancers, 2022 - mdpi.com
Simple Summary Chronic inflammation is known to drive cancer initiation and progression in
the liver and other organs. In different genetic mouse models, the role of the pro …