Background There is growing evidence that Bit1 exerts different roles in the development
and progression of human cancers. Although Bit1 was highly exhibited in ESCC tissues in …

Abstract Transducer of ErbB-2.1 (Tob1), a tumor suppressor protein, is inactivated in a
variety of cancers including stomach cancer. However, the role of Tob1 in gastric …

To analyze the expression of the transforming acidic coiled-coil protein 3 (TACC3) in
esophageal squamous cell carcinoma (ESCC) samples, and to identify whether TACC3 can …

Objective: To investigate the expression, significance, and role of transforming growth factor
β-activated kinase 1 (TAK1) in human thyroid cancer tissue. Methods: The data of 101 …

Colorectal cancer (CRC) is one of the most lethal cancers worldwide. The expression of β-
arrestin2 (β-Arr2, ARRB2) in CRC has been well investigated; however, its exact mechanism …

Transforming growth factor-β (TGFβ)-activated kinase 1 (TAK1) plays a central role in
controlling the cellular pro-inflammatory response via the activation of the nuclear factor κB …

Formation of metastases is the major cause of death in patients diagnosed with cancer. It is
a complex multistep process, including tumor cell migration, intravasation, survival in the …

Background TAB182 is overexpressed in cancerous tissues and correlated with poor overall
survival in lung cancer patients. Mechanistically, TAB182 participates in DNA damage repair …

Cancer stem cells are a key population participating in the promotion of the cervical cancer
progression through interacting with cancer cells. Existing studies have preliminary revealed …

Esophageal squamous cell carcinoma (ESCC) is one of the most common malignancies
worldwide. It is very urgent to understand the underlying molecular mechanism and develop …