Chemiluminescent 1, 2‐Dioxetane Iridium Complexes for Near‐Infrared Oxygen Sensing

HN Kagalwala, J Gerberich, CJ Smith… - Angewandte …, 2022 - Wiley Online Library
Chemiluminescent iridium‐based sensors which demonstrate oxygen dependent responses
have been developed. The molecular probes, named IrCL‐1, IrCL‐2 and IrCL‐3 consist of …

Dual-phosphorescent iridium (III) complexes extending oxygen sensing from hypoxia to hyperoxia

KY Zhang, P Gao, G Sun, T Zhang, X Li… - Journal of the …, 2018 - ACS Publications
Hypoxia and hyperoxia, referring to states of biological tissues in which oxygen supply is in
sufficient and excessive, respectively, are often pathological conditions. Many luminescent …

Iridium luminophore complexes for unimolecular oxygen sensors

MC DeRosa, DJ Hodgson, GD Enright… - Journal of the …, 2004 - ACS Publications
In this study, a series of novel luminescent cyclometalated Ir (III) complexes has been
synthesized and evaluated for use in unimolecular oxygen-sensing materials. The …

Intracellular and in vivo oxygen sensing using phosphorescent iridium (III) complexes

S Tobita, T Yoshihara - Current opinion in chemical biology, 2016 - Elsevier
Highlights•Optical probes are useful for quantification of oxygen level in cells and
tissues.•Iridium complexes can be used as organelle-specific oxygen probe.•Iridium …

Phosphorescent light–emitting iridium complexes serve as a hypoxia-sensing probe for tumor imaging in living animals

S Zhang, M Hosaka, T Yoshihara, K Negishi, Y Iida… - Cancer research, 2010 - AACR
Iridium complex is a promising organic light–emitting diode material for next generation
video displays that emits phosphorescence quenched by oxygen. We used this oxygen …

Ratiometric molecular sensor for monitoring oxygen levels in living cells

T Yoshihara, Y Yamaguchi, M Hosaka… - Angewandte Chemie …, 2012 - Wiley Online Library
Oxygen (dioxygen) is one of the key metabolites in aerobic organisms.[1] In cellular
respiration, oxygen plays a major role as the terminal acceptor of the electron transport …

Intracellular and in vivo oxygen sensing using phosphorescent Ir (III) complexes with a modified acetylacetonato ligand

T Yoshihara, M Hosaka, M Terata, K Ichikawa… - Analytical …, 2015 - ACS Publications
Small luminescent molecular probes based on the iridium (III) complex BTP,(btp) 2Ir
(acac)(btp= benzothienylpyridine, acac= acetylacetone) have been developed for sensing …

Synthesis, Characterization, and Evaluation of [Ir(ppy)2(vpy)Cl] as a Polymer-Bound Oxygen Sensor

MC DeRosa, PJ Mosher, GPA Yap… - Inorganic …, 2003 - ACS Publications
This study reports new luminescent oxygen sensors in which the luminophore is covalently
bound to the polymer matrix and compares their behavior to related sensors in which the …

Ultrabright oxygen optodes based on cyclometalated iridium (III) coumarin complexes

SM Borisov, I Klimant - Analytical Chemistry, 2007 - ACS Publications
Cyclometalated iridium (III) coumarin complexes represent new types of probes for optical
oxygen sensing. In comparison to the most commonly used ruthenium (II) polypyridyl dyes …

Phosphorescent NIR emitters for biomedicine: Applications, advances and challenges

PS Chelushkin, JR Shakirova, IS Kritchenkov… - Dalton …, 2022 - pubs.rsc.org
Application of NIR (near-infrared) emitting transition metal complexes in biomedicine is a
rapidly developing area of research. Emission of this class of compounds in the “optical …