Pathological and therapeutic advances in Parkinson's disease: mitochondria in the interplay
P Naren, A Cholkar, S Kamble, SS Khan… - Journal of …, 2023 - content.iospress.com
Parkinson's disease (PD) is the second most common neurodegenerative illness majorly
affecting the population between the ages of 55 to 65 years. Progressive dopaminergic …
affecting the population between the ages of 55 to 65 years. Progressive dopaminergic …
Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease
Mitochondrial dysfunction is one of the most early and prominent features in vulnerable
neurons in the brain of Alzheimer's disease (AD) patients. Recent studies suggest that …
neurons in the brain of Alzheimer's disease (AD) patients. Recent studies suggest that …
Alterations in mitochondrial quality control in Alzheimer's disease
Q Cai, P Tammineni - Frontiers in cellular neuroscience, 2016 - frontiersin.org
Mitochondrial dysfunction is one of the earliest and most prominent features in the brains of
Alzheimer's disease (AD) patients. Recent studies suggest that mitochondrial dysfunction …
Alzheimer's disease (AD) patients. Recent studies suggest that mitochondrial dysfunction …
Mitochondria in Alzheimer's disease and their potential role in Alzheimer's proteostasis
IW Weidling, RH Swerdlow - Experimental neurology, 2020 - Elsevier
Alzheimer's disease (AD) is a progressive brain disorder characterized by memory loss and
the accumulation of two insoluble protein aggregates, tau neurofibrillary tangles and beta …
the accumulation of two insoluble protein aggregates, tau neurofibrillary tangles and beta …
Mitochondrial dysfunction-the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-β toxicity
The pathology of Alzheimer's disease (AD) is characterized by amyloid plaques (aggregates
of amyloid-β (Aβ)) and neurofibrillary tangles (aggregates of tau) and is accompanied by …
of amyloid-β (Aβ)) and neurofibrillary tangles (aggregates of tau) and is accompanied by …
Mitochondrial dysfunction in Alzheimer's disease: Role in pathogenesis and novel therapeutic opportunities
JM Perez Ortiz, RH Swerdlow - British journal of pharmacology, 2019 - Wiley Online Library
Dysfunction of cell bioenergetics is a common feature of neurodegenerative diseases, the
most common of which is Alzheimer's disease (AD). Disrupted energy utilization implicates …
most common of which is Alzheimer's disease (AD). Disrupted energy utilization implicates …
Insights into the pathogenesis of neurodegenerative diseases: Focus on mitochondrial dysfunction and oxidative stress
A Jurcau - International journal of molecular sciences, 2021 - mdpi.com
As the population ages, the incidence of neurodegenerative diseases is increasing. Due to
intensive research, important steps in the elucidation of pathogenetic cascades have been …
intensive research, important steps in the elucidation of pathogenetic cascades have been …
Mitochondrial function and abnormalities implicated in the pathogenesis of ASD
FJ Castora - Progress in Neuro-Psychopharmacology and …, 2019 - Elsevier
Mitochondria are the powerhouse that generate over 90% of the ATP produced in cells. In
addition to its role in energy production, the mitochondrion also plays a major role in …
addition to its role in energy production, the mitochondrion also plays a major role in …
Role of mitochondrial amyloid-β in Alzheimer's disease
JX Chen, SS Yan - Journal of Alzheimer's Disease, 2010 - content.iospress.com
Mitochondrial dysfunction is an early feature of Alzheimer's disease (AD). Abnormalities in
mitochondrial properties include impaired energy metabolism, defects in key respiratory …
mitochondrial properties include impaired energy metabolism, defects in key respiratory …
Mitochondrial dysfunction: cause and consequence of Alzheimer's disease
K Friedland-Leuner, C Stockburger, I Denzer… - Progress in molecular …, 2014 - Elsevier
The etiology of common, nonfamiliar late-onset Alzheimer's disease (LOAD) is only partly
understood and seems to be extremely complex including many genetic and environmental …
understood and seems to be extremely complex including many genetic and environmental …