Potassium channels govern duration and frequency of excitable membrane events and may
regulate signals that are important in neuronal development. This study assesses the …

Voltage-gated Ca2+ channels provide a mode of Ca2+ influx that is essential for intracellular
signaling in many cells. Semi-quantitative reverse transcription-polymerase chain reaction …

Different types of K+ channels play important roles in many aspects of excitability. The
isolation of cDNA clones from Drosophila, Aplysia, Xenopus, and mammals points to a large …

Developmental changes in neuronal excitability reflect the regulated expression of ion
channels and receptors. Purkinje neurons of the rat cerebellum progress from slow irregular …

Calcium transients play an important role in the early and later phases of differentiation and
maturation of single neurons and neuronal networks. Small-conductance calcium-activated …

K+ channels regulate diverse aspects of cellular function especially in excitable tissues. It
has recently been shown that voltage sensitive K+ channels are encoded by a superfamily …

During neuronal differentiation and maturation, electrical excitability is essential for proper
gene expression and the formation of synapses. The expression of ion channels is crucial …

Hippocampal neurons are highly plastic in their excitable properties, both during
development and in the adult brain. As voltage-sensitive K+ channels are major …

K+ channels are major determinants of membrane excitability. Differences in neuronal
excitability within the nervous system may arise from differential expression of K+ channel …

A developmental increase in delayed rectifier potassium current (I Kv) in embryonic
Xenopus spinal neurons is critical for the maturation of excitability and action potential …