The calcium-sensing receptor (CaSR), a cell-surface sensor for Ca2+, is the master
regulator of calcium homeostasis in humans and is the target of calcimimetic drugs for the …

The calcium-sensing receptor (CaSR) is a family C G-protein-coupled receptor (GPCR) that
has a central role in regulating systemic calcium homeostasis,. Here we use cryo-electron …

Abstract The Ca 2+-sensing receptor (the CaSR), a G-protein-coupled receptor, regulates
Ca 2+ homeostasis in the body by monitoring extracellular levels of Ca 2+([Ca 2+] o) and …

Calcium-sensing receptor (CaSR) is a class CG protein–coupled receptor (GPCR) that plays
an important role in calcium homeostasis and parathyroid hormone secretion. Here, we …

Abstract Calcium-sensing receptor (CASR), expressed in parathyroid gland and kidney, is a
critical regulator of extracellular calcium homeostasis. This G protein-coupled receptor exists …

The human extracellular calcium-sensing (CaS) receptor controls plasma Ca2+ levels and
contributes to nutrient-dependent maintenance and metabolism of diverse organs. Allosteric …

The calcium-sensing receptor (CaSR) is a G protein-coupled receptor that plays a key role in
calcium homeostasis, by sensing free calcium levels in blood and regulating parathyroid …

The calcium-sensing receptor (CASR) is expressed in parathyroid hormone (PTH)-secreting
cells of the parathyroid gland and cells lining the renal tubule. The activated CASR …

Ca2+-sensing receptors (CaSRs) modulate calcium and magnesium homeostasis and many
(patho) physiological processes by responding to extracellular stimuli, including divalent …

Calcium-sensing receptors (CaSRs) regulate systemic calcium homeostasis in the
parathyroid gland, kidney, intestine, and bone and translate fluctuations in serum calcium …