Human spinal oligodendrogenic neural progenitor cells enhance pathophysiological outcomes and functional recovery in a clinically relevant cervical spinal cord …
K Pieczonka, H Nakashima, N Nagoshi… - Stem Cells …, 2023 - academic.oup.com
Traumatic spinal cord injury (SCI) results in the loss of neurons, oligodendrocytes, and
astrocytes. Present interventions for SCI include decompressive surgery, anti-inflammatory …
astrocytes. Present interventions for SCI include decompressive surgery, anti-inflammatory …
Human spinal oligodendrogenic neural progenitor cells promote functional recovery after spinal cord injury by axonal remyelination and tissue sparing
N Nagoshi, M Khazaei, JE Ahlfors… - Stem cells …, 2018 - academic.oup.com
Cell transplantation therapy utilizing neural precursor cells (NPCs) is a conceptually
attractive strategy for traumatic spinal cord injury (SCI) to replace lost cells, remyelinate …
attractive strategy for traumatic spinal cord injury (SCI) to replace lost cells, remyelinate …
Neural stem cell therapies for spinal cord injury repair: an update on recent preclinical and clinical advances
SM Hosseini, B Borys, S Karimi-Abdolrezaee - Brain, 2024 - academic.oup.com
Traumatic spinal cord injury (SCI) is a leading cause of lifelong disabilities. Permanent
sensory, motor and autonomic impairments after SCI are substantially attributed to …
sensory, motor and autonomic impairments after SCI are substantially attributed to …
Regenerative replacement of neural cells for treatment of spinal cord injury
WB McIntyre, K Pieczonka, M Khazaei… - Expert Opinion on …, 2021 - Taylor & Francis
ABSTRACT Introduction: Traumatic Spinal Cord Injury (SCI) results from primary physical
injury to the spinal cord, which initiates a secondary cascade of neural cell death. Current …
injury to the spinal cord, which initiates a secondary cascade of neural cell death. Current …
Neural precursor cell transplantation enhances functional recovery and reduces astrogliosis in bilateral compressive/contusive cervical spinal cord injury
JT Wilcox, K Satkunendrarajah… - Stem Cells …, 2014 - academic.oup.com
Spinal cord injury has a significant societal and personal impact. Although the majority of
injuries involve the cervical spinal cord, few studies of cell transplantation have used …
injuries involve the cervical spinal cord, few studies of cell transplantation have used …
[HTML][HTML] Transplantation of human induced pluripotent stem cell-derived neural progenitor cells promotes forelimb functional recovery after cervical spinal cord injury
Y Zheng, CM Gallegos, H Xue, S Li, DH Kim, H Zhou… - Cells, 2022 - mdpi.com
Locomotor function after spinal cord injury (SCI) is critical for assessing recovery. Currently,
available means to improve locomotor function include surgery, physical therapy …
available means to improve locomotor function include surgery, physical therapy …
[HTML][HTML] Advances in neural stem cell therapy for spinal cord injury: safety, efficacy, and future perspectives
S Lee, H Nam, KM Joo, SH Lee - Neurospine, 2022 - ncbi.nlm.nih.gov
Spinal cord injury (SCI) is a devastating central nervous system injury that leads to severe
disabilities in motor and sensory functions, causing significant deterioration in patients' …
disabilities in motor and sensory functions, causing significant deterioration in patients' …
[HTML][HTML] Adult neural progenitor cells transplanted into spinal cord injury differentiate into oligodendrocytes, enhance myelination, and contribute to recovery
SR Sankavaram, R Hakim, R Covacu, A Frostell… - Stem Cell Reports, 2019 - cell.com
Long-term survival and integration of neural progenitor cells (NPCs) transplanted following
spinal cord injury (SCI) have been observed. However, questions concerning the …
spinal cord injury (SCI) have been observed. However, questions concerning the …
[HTML][HTML] Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in an Early Chronic Spinal coRd Injury NOD-scid Mouse Model
DL Salazar, N Uchida, FPT Hamers, BJ Cummings… - PloS one, 2010 - journals.plos.org
Background Traumatic spinal cord injury (SCI) results in partial or complete paralysis and is
characterized by a loss of neurons and oligodendrocytes, axonal injury, and demyelination …
characterized by a loss of neurons and oligodendrocytes, axonal injury, and demyelination …
Human embryonic stem cell-derived oligodendrocyte progenitor cells: preclinical efficacy and safety in cervical spinal cord injury
NC Manley, CA Priest, J Denham… - Stem cells …, 2017 - academic.oup.com
Cervical spinal cord injury (SCI) remains an important research focus for regenerative
medicine given the potential for severe functional deficits and the current lack of treatment …
medicine given the potential for severe functional deficits and the current lack of treatment …
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