Modulation of adiponectin as a potential therapeutic strategy

S Lim, MJ Quon, KK Koh - Atherosclerosis, 2014 - Elsevier
Adiponectin is produced predominantly by adipocytes and plays an important role in
metabolic and cardiovascular homeostasis through its insulin-sensitizing actions and anti …

Adiponectin: Identification, physiology and clinical relevance in metabolic and vascular disease

Y Matsuzawa - Atherosclerosis supplements, 2005 - Elsevier
Adiponectin is the most abundant adipose-specific protein. Its expression is reduced in
obesity, insulin resistance and type 2 diabetes, and plasma concentrations are inversely …

Adiponectin, a unique adipocyte-derived factor beyond hormones

N Maeda, T Funahashi, Y Matsuzawa, I Shimomura - Atherosclerosis, 2020 - Elsevier
Visceral fat accumulation has a marked impact on atherosclerotic cardiovascular diseases
and metabolic syndrome clustering diabetes, dyslipidemia, and hypertension. Adiponectin …

The role of adiponectin in maintaining metabolic homeostasis

SC Adiyaman, M Ozer, BO Saydam… - Current Diabetes …, 2020 - ingentaconnect.com
Background: Adiponectin is an adipocyte-derived cytokine closely associated with obesity,
altered body adipose tissue distribution, insulin resistance, and cardiovascular diseases …

Beneficial effects of adiponectin on glucose and lipid metabolism and atherosclerotic progression: mechanisms and perspectives

H Yanai, H Yoshida - International journal of molecular sciences, 2019 - mdpi.com
Circulating adiponectin concentrations are reduced in obese individuals, and this reduction
has been proposed to have a crucial role in the pathogenesis of atherosclerosis and …

Adiponectin: a potential therapeutic target for metabolic syndrome

AA Ghadge, AA Khaire, AA Kuvalekar - Cytokine & growth factor reviews, 2018 - Elsevier
Adiponectin is an important adipocytokine secreted chiefly by fat containing adipocytes, and
plays a crucial role in glucose and lipid metabolism, inflammation and oxidative stress …

Mechanisms of adiponectin regulation and use as a pharmacological target

SA Phillips, JT Kung - Current opinion in pharmacology, 2010 - Elsevier
Adiponectin is an insulin-sensitizing and anti-inflammatory fat cell hormone that has
immense potential as a therapeutic target for a multitude of obesity-associated diseases …

The role of adiponectin in obesity, diabetes, and cardiovascular disease

J Kawano, R Arora - Journal of the cardiometabolic syndrome, 2009 - Wiley Online Library
Nearly 1 in 4 adults in the United States is obese. The connection between obesity and
insulin resistance, type 2 diabetes, and cardiovascular disease is a well researched one …

Adiponectin: regulation of its production and its role in human diseases

A Shehzad, W Iqbal, O Shehzad, YS Lee - Hormones, 2012 - Springer
Adiponectin is a white and brown adipose tissue hormone, also known as gelatin-binding
protein-28 (GBP28), AdipoQ, adipocyte complement-related protein (ACRP30), or apM1 …

Adiponectin: a new link between obesity, insulin resistance and cardiovascular disease

X Palomer, A Pérez, F Blanco-Vaca - Medicina clinica, 2005 - europepmc.org
Adiponectin is a novel and important member of the adipocytokine family which has
regulatory functions in the glucose and lipid metabolism. Adiponectin stimulates fatty acids …