Background Gram-positive spectrum antibiotics such as vancomycin, teicoplanin,
daptomycin, and linezolid are frequently used in empirical treatment combinations in …

Background Antibiotic stewardship programmes have a pivotal role in ICUs, but the level of
implementation of these programmes at the regional or national level is not well known …

Objective The purpose of this study was to describe antimicrobial utilization, consumption,
indications and microbial resistance in a medical-surgical-trauma intensive care unit (ICU) of …

Objectives There is little evidence and few guidelines to inform the most appropriate dosing
and monitoring for antimicrobials in the ICU. We aimed to survey current practices around …

International-predominantly American-studies undertaken in the ICUs of teaching centres
show that inadequate antibiotic therapy increases mortality and length of stay. We sought to …

Background Mandatory indications for antimicrobial agents are recommended by a number
of organizations to act as a force function, requiring prescribers to provide a reason for …

Background Several strategies to optimise the use of antibiotics have been developed. Most
of these interventions can be classified as educational or restrictive. Restrictive measures …

Antibiotic use in the intensive care unit (ICU) presents unique challenges due to the high
acuity and complexity of critically ill patients. Inappropriate use of antibiotics can contribute …

Background Assessment of antimicrobial use places an emphasis on therapeutic aspects of
infected patients. Our aim was to determine the risk factors for unnecessary antibiotic …

Background Intensive care units (ICUs) are specialized units where patients with critical
conditions are admitted for getting specialized and individualized medical treatment. High …