Maintenance of a normal serum phosphate level depends on absorption in the gut,
reabsorption and excretion by the kidney, and the flux between the extracellular and skeletal …

Chronic kidney disease (CKD)–mineral and bone disorder is associated with diverse
metabolic and endocrine disturbances that ultimately may contribute to further loss of kidney …

Maintenance of phosphate balance is essential for life, and mammals have developed a
sophisticated system to regulate phosphate homeostasis over the course of evolution …

Consequences and management of hyperphosphatemia in patients with renal insufficiency.
Progressive renal insufficiency leads to hyperphosphatemia, hypocalcemia, and secondary …

Hyperphosphatemia is a common complication in patients with chronic kidney disease
(CKD), particularly in those requiring renal replacement therapy. The importance of …

Phosphate retention and, later, hyperphosphatemia are key contributors to chronic kidney
disease (CKD)–mineral and bone disorder (MBD). Phosphate homeostatic mechanisms …

New advances in the pathogenesis of renal osteodystrophy (ROD) change the perspective
from which many of its features and treatment are viewed. Calcium, phosphate, parathyroid …

Chronic kidney disease mineral bone disorder (CKD-MBD) is a common co-morbidity in
patients with CKD. Characterized by laboratory abnormalities, bone abnormality, and …

Hyperphosphatemia has consistently been shown to be associated with dismal outcome in a
wide variety of populations, particularly in chronic kidney disease (CKD). Compelling …

Hyperphosphatemia is a nearly universal complication of end-stage renal disease that is
widely recognized as one of the most important and most challenging clinical targets to meet …