Real‐world effectiveness of Azvudine versus nirmatrelvir–ritonavir in hospitalized patients with COVID‐19: A retrospective cohort study
G Deng, D Li, Y Sun, L Jin, Q Zhou… - Journal of medical …, 2023 - Wiley Online Library
Chinese guidelines prioritize the use of Azvudine and nirmatrelvir–ritonavir in COVID‐19
patients. Nevertheless, the real‐world effectiveness of Azvudine versus nirmatrelvir–ritonavir …
patients. Nevertheless, the real‐world effectiveness of Azvudine versus nirmatrelvir–ritonavir …
Paxlovid associated with decreased hospitalization rate among adults with COVID-19—United States, April–September 2022
MM Shah, B Joyce, ID Plumb, S Sahakian… - American Journal of …, 2023 - amjtransplant.org
Paxlovid associated with decreased hospitalization rate among adults with COVID-19 —
United States, April–September 2022 - American Journal of Transplantation Skip to Main …
United States, April–September 2022 - American Journal of Transplantation Skip to Main …
Association of Molnupiravir and Nirmatrelvir-Ritonavir with preventable mortality, hospital admissions and related avoidable healthcare system cost among high-risk …
Background Real-world data is currently limited on the association between oral antiviral
therapy and healthcare system burden in patients with mild-to-moderate COVID-19. This …
therapy and healthcare system burden in patients with mild-to-moderate COVID-19. This …
Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label …
Background The safety, effectiveness, and cost-effectiveness of molnupiravir, an oral
antiviral medication for SARS-CoV-2, has not been established in vaccinated patients in the …
antiviral medication for SARS-CoV-2, has not been established in vaccinated patients in the …
[HTML][HTML] The role of antiviral treatment in the COVID-19 pandemic
TK Burki - The Lancet Respiratory Medicine, 2022 - thelancet.com
On Dec 22, 2021, the US Food and Drug Administration (FDA) issued an emergency use
authorisation for Pfizer's COVID-19 antiviral, Paxlovid. Trial results released by the …
authorisation for Pfizer's COVID-19 antiviral, Paxlovid. Trial results released by the …
[HTML][HTML] Population-based evaluation of the effectiveness of nirmatrelvir–ritonavir for reducing hospital admissions and mortality from COVID-19
Background: A randomized controlled trial involving a high-risk, unvaccinated population
that was conducted before the Omicron variant emerged found that nirmatrelvir–ritonavir …
that was conducted before the Omicron variant emerged found that nirmatrelvir–ritonavir …
[HTML][HTML] Antiviral drug treatment for nonsevere COVID-19: a systematic review and network meta-analysis
T Pitre, R Van Alstine, G Chick, G Leung, D Mikhail… - Cmaj, 2022 - Can Med Assoc
Background: Randomized trial evidence suggests that some antiviral drugs are effective in
patients with COVID-19. However, the comparative effectiveness of antiviral drugs in …
patients with COVID-19. However, the comparative effectiveness of antiviral drugs in …
Innovative randomized phase I study and dosing regimen selection to accelerate and inform pivotal COVID‐19 trial of nirmatrelvir
RSP Singh, SS Toussi, F Hackman… - Clinical …, 2022 - Wiley Online Library
Coronavirus disease 2019 (COVID‐19) is a continued leading cause of hospitalization and
death. Safe, efficacious COVID‐19 antivirals are needed urgently. Nirmatrelvir (PF …
death. Safe, efficacious COVID‐19 antivirals are needed urgently. Nirmatrelvir (PF …
Comparing molnupiravir and nirmatrelvir/ritonavir efficacy and the effects on SARS-CoV-2 transmission in animal models
Therapeutic options against SARS-CoV-2 are underutilized. Two oral drugs, molnupiravir
and paxlovid (nirmatrelvir/ritonavir), have received emergency use authorization. Initial trials …
and paxlovid (nirmatrelvir/ritonavir), have received emergency use authorization. Initial trials …
Viral burden rebound in hospitalised patients with COVID-19 receiving oral antivirals in Hong Kong: a population-wide retrospective cohort study
Background Viral rebound after nirmatrelvir–ritonavir treatment has implications for the
clinical management and isolation of patients with COVID-19. We evaluated an unselected …
clinical management and isolation of patients with COVID-19. We evaluated an unselected …