Studies in two areas of biology have pointed to the existence of cellular genes that exhibit an
oncogenic potential after activation. These normal cellular genes, sometimes termed “proto …

Overview Retroviral oncogenes originally were derived from genes in eukaryotic cells. The
seminal discovery that DNA sequences within normal, uninfected, nonmalignant cells were …

In recent years cellular homologues of many viral oncogenes have been identified. As these
genes are partially homologous to viral oncogenes and are activated in some tumour cell …

Theoretically, the cancerous phenotype of cells can result from epigenetic or biochemical
regulatory changes without alteration of the genotype. Although epigenetic changes may …

In the past few years and with increasing momentum, it is becoming clear that the keys to
understanding normal processes might be found in those genes, collectively termed …

For many years a genetic basis has been postulated for cancers and leukaemias. However,
this concept has now been strengthened by the discovery of a group of genes (oncogenes) …

The development of a unifying model or concept to explain seemingly highly divers
phenomenons in nature is often considered as a true sign for important scientific progress …

Oncogenes. - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC
Menu About Tools Developers Help Contact us Helpdesk Feedback Twitter Blog Tech blog …

The search for the genetic targets responsible for tumorigenesis has led to the identification
of a number of cancer genes or cellular oncogenes (c-oncogenes). The oncogenes are …

Cancer cells harbor both dominant and recessive genetic damage arising from point
mutations and large rearrangements of DNA that may distort either the expression or the …