[HTML][HTML] TERT promoter mutations and tumor persistence/recurrence in papillary thyroid cancer

JK Myung, BK Kwak, JA Lim… - Cancer research and …, 2016 - synapse.koreamed.org
Purpose A telomerase reverse transcriptase (TERT) promoter mutation was identified in
thyroid cancer. This TERT promoter mutation is thought to be a prognostic molecular marker …

Prognostic Significance of TERT Promoter Mutations in Papillary Thyroid Carcinomas in a BRAFV600E Mutation–Prevalent Population

SE Lee, TS Hwang, YL Choi, HS Han, WS Kim… - Thyroid, 2016 - liebertpub.com
Background: The role of telomerase reverse transcriptase (TERT) promoter mutations in
differentiated thyroid cancer has been well established. These mutations have a significantly …

TERT mRNA Expression as a Novel Prognostic Marker in Papillary Thyroid Carcinomas

A Tanaka, M Matsuse, V Saenko, T Nakao… - Thyroid, 2019 - liebertpub.com
Background: Telomerase reverse transcriptase (TERT) promoter mutations have been found
in a subset of papillary thyroid carcinomas (PTCs) and are associated with tumor …

Clinicopathological indicators for TERT promoter mutation in papillary thyroid carcinoma

HY Na, HW Yu, W Kim, JH Moon, CH Ahn… - Clinical …, 2022 - Wiley Online Library
Objective Mutations in the telomerase reverse transcriptase (TERT) promoter have been
reported as a convincing prognostic factor in papillary thyroid carcinomas (PTCs). We aimed …

[PDF][PDF] Low prevalence of somatic TERT promoter mutations in classic papillary thyroid carcinoma

MJ Jeon, WG Kim, S Sim, S Lim… - Endocrinology and …, 2016 - synapse.koreamed.org
Background: Transcriptional activating mutations of telomerase reverse transcriptase (TERT)
are associated with more aggressive thyroid cancer. We evaluated the significance of TERT …

Telomerase reverse transcriptase mutations are independent predictor of disease‐free survival in M iddle E astern papillary thyroid cancer

R Bu, AK Siraj, SP Divya, Y Kong… - … journal of cancer, 2018 - Wiley Online Library
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Tumor
recurrence occurs in∼ 20% of PTCs and some reach advanced stages. Promoter mutation …

In Japanese patients with papillary thyroid carcinoma, TERT promoter mutation is associated with poor prognosis, in contrast to BRAF V600E mutation

A Nasirden, T Saito, Y Fukumura, K Hara, K Akaike… - Virchows Archiv, 2016 - Springer
The prognostic value of BRAF V600E and TERT promoter mutation in papillary thyroid
carcinoma (PTC) is controversial. We examined alterations in BRAF V600E and TERT …

[HTML][HTML] TERT promoter and BRAF V600E mutations in papillary thyroid cancer: a single-institution experience in Korea

MJ Kim, JK Kim, GJ Kim, SW Kang, J Lee, JJ Jeong… - Cancers, 2022 - mdpi.com
Simple Summary TERT promoter mutation has recently emerged as a promising prognostic
biomarker for aggressive papillary thyroid cancer (PTC), along with BRAF B600E mutation …

TERT Promoter Mutations Increase Tumor Aggressiveness by Altering TERT mRNA Splicing in Papillary Thyroid Carcinoma

A Sako, M Matsuse, V Saenko, A Tanaka… - The Journal of …, 2024 - academic.oup.com
Context Telomerase reverse transcriptase promoter (TERT-p) mutations, which upregulate
TERT expression, are strongly associated with tumor aggressiveness and worse prognosis …

TERT promoter mutations are associated with distant metastases in papillary thyroid carcinoma

G Gandolfi, M Ragazzi, A Frasoldati… - European Journal of …, 2015 - academic.oup.com
Objective Transcriptional activating mutations in the promoter of the telomerase reverse
transcriptase (TERT) gene were reported at high frequency in aggressive poorly …