Relation of human papilloma virus status to cervical lesions and consequences for cervical-cancer screening: a prospective study

MAE Nobbenhuis, JMM Walboomers, TJM Helmerhorst… - The Lancet, 1999 - thelancet.com
Background A relation has been established between infection with high-risk types of
human papillomavirus and development of cervical cancer. We investigated a role for testing …

Human papillomavirus testing in primary cervical screening

J Cuzick, A Szarewski, G Terry, A Hanby, P Maddox… - The Lancet, 1995 - thelancet.com
Several studies have examined the role of tests for human papillomavirus (HPV) in
screening for cervical cancer but as yet the relevance is unclear. We looked at HPV testing …

Natural history of cervical human papillomavirus infection in young women: a longitudinal cohort study

CBJ Woodman, S Collins, H Winter, A Bailey, J Ellis… - The Lancet, 2001 - thelancet.com
Background Laboratory and epidemiological research suggests an association between
human papillomavirus (HPV) and cervical intraepithelial neoplasia (CIN). We studied the …

Viral load of human papillomavirus and risk of CIN3 or cervical cancer

AT Lorincz, PE Castle, ME Sherman, DR Scott… - The Lancet, 2002 - thelancet.com
Carcinogenic human papillomaviruses (HPV) are thought to be necessary for development
of cervical cancer. We assessed whether higher viral loads of such viruses predicted future …

Management of women who test positive for high-risk types of human papillomavirus: the HART study

J Cuzick, A Szarewski, H Cubie, G Hulman… - The Lancet, 2003 - thelancet.com
Background Certain types of human papillomavirus (HPV) are the primary cause of almost
all cervical cancers. HPV testing of cervical smears is more sensitive but less specific than …

Human papillomavirus type 18 and rapidly progressing cervical intraepithelial neoplasia

CBJ Woodman, S Collins, TP Rollason, H Winter… - The Lancet, 2003 - thelancet.com
Background Human papillomavirus type 18 (HPV-18) is the second most frequent of the
HPV types detected when squamous-cell cancer is diagnosed and the type most strongly …

Efficacy of human papillomavirus testing for the detection of invasive cervical cancers and cervical intraepithelial neoplasia: a randomised controlled trial

G Ronco, P Giorgi-Rossi, F Carozzi, M Confortini… - The lancet …, 2010 - thelancet.com
Background Human papillomavirus (HPV) testing is known to be more sensitive, but less
specific than cytology for detecting cervical intraepithelial neoplasia (CIN). We assessed the …

Cervical cancer risk for women undergoing concurrent testing for human papillomavirus and cervical cytology: a population-based study in routine clinical practice

HA Katki, WK Kinney, B Fetterman, T Lorey… - The lancet …, 2011 - thelancet.com
Background Concurrent testing for human papillomavirus (HPV) and cervical cytology (co-
testing) is an approved alternative to cytology alone in women aged 30 years and older. We …

Cytological regression and clearance of high-risk human papillomavirus in women with an abnormal cervical smear

MAE Nobbenhuis, TJM Helmerhorst… - The Lancet, 2001 - thelancet.com
We studied the natural course of high-risk human papillomavirus (HPV) infection and
cytological regression in women referred for colposcopy because of abnormal cervical …

Human papillomavirus type 16 DNA in cervical smears as predictor of high-grade cervical cancer

J Cuzick, G Terry, L Ho, T Hollingworth, M Anderson - The Lancet, 1992 - Elsevier
The management of women with mild to moderately dyskaryotic cervical smears would
benefit from a non-invasive test that predicts which women have high-grade cervical …