Phospholipid complex-loaded self-assembled phytosomal soft nanoparticles: evidence of enhanced solubility, dissolution rate, ex vivo permeability, oral bioavailability …

DR Telange, NK Sohail, AT Hemke, PS Kharkar… - Drug Delivery and …, 2021 - Springer
In this study, self-assembled phytosomal soft nanoparticles encapsulated with phospholipid
complex (MPLC SNPs) using a combination of solvent evaporation and nanoprecipitation …

Enhancing biopharmaceutical attributes of phospholipid complex-loaded nanostructured lipidic carriers of mangiferin: systematic development, characterization and …

RK Khurana, AK Bansal, S Beg, AJ Burrow… - International journal of …, 2017 - Elsevier
Mangiferin (Mgf), largely expressed out from the leaves and stem bark of Mango, is a potent
antioxidant. However, its in vivo activity gets tremendously reduced owing to poor aqueous …

Improving the biopharmaceutical attributes of mangiferin using vitamin E-TPGS co-loaded self-assembled phosholipidic nano-mixed micellar systems

RK Khurana, BL Gaspar, G Welsby, OP Katare… - Drug delivery and …, 2018 - Springer
The current research work encompasses the development, characterization, and evaluation
of self-assembled phospholipidic nano-mixed miceller system (SPNMS) of a poorly soluble …

Targeting mangiferin loaded N-succinyl chitosan-alginate grafted nanoparticles against atherosclerosis–A case study against diabetes mediated hyperlipidemia in rat

Y Wang, T Karmakar, N Ghosh, S Basak, NG Sahoo - Food Chemistry, 2022 - Elsevier
Mangiferin (MGF), from Mangifera indica is well reported for its hypoglycemic activity and
hypolipidemic activity. However, MGF suffers therapeutic limitation due to poor solubility …

Response surface optimization of microfluidic formulations of nanobilosomes for enhancement of aqueous solubility, digestive stability, and cellular antioxidant activity …

P Thiengkaew, S Thanitwatthanasak, S Srisala… - Food Chemistry, 2021 - Elsevier
Mangiferin-loaded nanobilosomes (MGF-NBSs) were developed using microfluidic-based
techniques to improve aqueous solubility, digestive stability, and cellular antioxidant activity …

Use of combined nanocarrier system based on chitosan nanoparticles and phospholipids complex for improved delivery of ferulic acid

DR Telange, SP Jain, AM Pethe, PS Kharkar… - International journal of …, 2021 - Elsevier
A novel nanocarrier system of phospholipids complex loaded chitosan nanoparticles
(FAPLC CNPs) was developed to improve the oral bioavailability and antioxidant potential of …

Ginkgolides-loaded soybean phospholipid-stabilized nanosuspension with improved storage stability and in vivo bioavailability

P Wang, X Cao, Y Chu - Colloids and Surfaces B: Biointerfaces, 2019 - Elsevier
The purpose of this study was to investigate the effects of soybean phospholipid, as a steric
stabilizer, on improving dissolution rate, storage stability and bioavailability of ginkgolides …

Lipid–polymer hybrid nanoparticles for oral delivery of tartary buckwheat flavonoids

J Zhang, D Wang, Y Wu, W Li, Y Hu… - Journal of agricultural …, 2018 - ACS Publications
Flavonoids rich in Tartary buckwheat (TBFs) are the acknowledged health-promoting
substances, even with the low oral bioavailability due to its chemical instability in …

Phytosome-nanosuspensions for silybin-phospholipid complex with increased bioavailability and hepatoprotection efficacy

C Chi, C Zhang, Y Liu, H Nie, J Zhou, Y Ding - European journal of …, 2020 - Elsevier
Silybin, a natural compound for treating liver disease, has been shown to provide diverse
biological activities such as anticancer, antioxidant and hepatoprotective. However, it is still …

Designing and fabrication of colloidal nano-phytosomes with gamma-oryzanol and phosphatidylcholine for encapsulation and delivery of polyphenol-rich extract from …

H Andishmand, M Yousefi, N Jafari… - International Journal of …, 2024 - Elsevier
Nano-carriers are well-known delivery systems to encapsulate different bioactive
compounds and extracts. Such nano-systems are used in various food and drug areas to …