Aripiprazole for relapse prevention and craving in alcohol use disorder: current evidence and future perspectives

G Martinotti, L Orsolini, M Fornaro… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: Among other approaches, the modulation of the dopaminergic pathway has
been advocated in the therapeutic management of Alcohol Use Disorders (AUD). A potential …

Aripiprazole for relapse prevention and craving in alcohol-dependent subjects: results from a pilot study

L Janiri, G Martinotti, M Di Nicola - Journal of clinical …, 2007 - journals.lww.com
Aripiprazole for Relapse Prevention and Craving in Alcohol-D... : Journal of Clinical
Psychopharmacology Aripiprazole for Relapse Prevention and Craving in Alcohol-Dependent …

Aripiprazole: a drug with a novel mechanism of action and possible efficacy for alcohol dependence

DE Vergne, RF Anton - … (Formerly Current Drug Targets-CNS & …, 2010 - ingentaconnect.com
Alcohol dependence is a costly and socially devastating illness. The dopamine system has
received increased attention due to the consensus that dopaminergic dysfunction is at the …

Aripiprazole effects on alcohol consumption and subjective reports in a clinical laboratory paradigm—possible influence of self‐control

K Voronin, P Randall, H Myrick… - Alcoholism: Clinical and …, 2008 - Wiley Online Library
Introduction: There has been increasing interest in the use of medications that affect the
dopamine receptor in the treatment of alcoholism. Aripiprazole has the unique …

A randomized, multicenter, double-blind, placebo-controlled study of the efficacy and safety of aripiprazole for the treatment of alcohol dependence

RF Anton, H Kranzler, C Breder… - Journal of clinical …, 2008 - journals.lww.com
The purpose of this study was to compare the efficacy and safety of aripiprazole with
placebo in the treatment of alcoholics. In this 12-week multicenter, double-blind study, 295 …

Rationale for use of aripiprazole for alcohol dependence treatment

GA Kenna - Drugs Future, 2003 - access.portico.org
Given the broad implications for alcoholism in many societies, the major aims of drug
development in the field of pharmacotherapy for alcohol dependence involve finding …

Aripiprazole in the treatment of patients with alcohol dependence: a double-blind, comparison trial vs. naltrexone

G Martinotti, M Di Nicola… - Journal of …, 2009 - journals.sagepub.com
Substantial evidence suggests that both partial dopamine agents and mixed 5-HT1A/2A
receptor drugs independently show significant efficacy in reducing alcohol use in both …

[PDF][PDF] Aripiprazole, alcohol and substance abuse: a review.

M Brunetti, L DI TIZIO, S Dezi, G Pozzi… - European Review for …, 2012 - europeanreview.org
Aripiprazole is an atypical an-tipsychotic used for schizophrenia, manic and mixed episodes
associated with bipolar I disorder and as adjunctive therapy for major depressive disorder. It …

Effects of aripiprazole on subjective and physiological responses to alcohol

HR Kranzler, J Covault… - Alcoholism: clinical …, 2008 - Wiley Online Library
Background: Aripiprazole is an atypical antipsychotic with partial agonist activity at D2
receptors, which could reduce the reinforcing effects of alcohol. The present study examined …

A safety and tolerability laboratory study of the combination of aripiprazole and topiramate in volunteers who drink alcohol

GA Kenna, L Leggio, RM Swift - … : Clinical and Experimental, 2009 - Wiley Online Library
Objective There are no reports examining the safety of taking both topiramate and
aripiprazole together with alcohol. The ultimate aim for this research is to determine whether …