Heterozygous mutations in FOXP2, which encodes a forkhead transcription factor, have
been shown to cause developmental verbal dyspraxia and language impairment. FOXP2 …

Heterozygous mutations of the human FOXP2 gene cause a developmental disorder
involving impaired learning and production of fluent spoken language. Previous …

Language is a defining characteristic of the human species, but its foundations remain
mysterious. Heritable disorders offer a gateway into biological underpinnings, as illustrated …

Heterozygous mutations of the human FOXP2 transcription factor gene cause the best-
described examples of monogenic speech and language disorders. Acquisition of proficient …

The closely related paralogues FOXP2 and FOXP1 encode transcription factors with shared
functions in the development of many tissues, including the brain. However, while mutations …

Heterozygous mutations of the human FOXP2 gene are implicated in a severe speech and
language disorder. Aetiological mutations of murine Foxp2 yield abnormal synaptic plasticity …

Could a mutation in a single gene be the evolutionary lynchpin supporting the development
of human language? A rare mutation in the molecule known as FOXP2 discovered in a …

The most well-described example of an inherited speech and language disorder is that
observed in the multigenerational KE family, caused by a heterozygous missense mutation …

A rare mutation affecting the Forkhead-box protein P2 (FOXP2) transcription factor causes a
severe monogenic speech and language disorder. Mice carrying an identical point mutation …

Previous studies have demonstrated that mutation in the forkhead domain of the forkhead
box P2 (FOXP2) protein (R553H) causes speech-language disorders. To further analyze …