Neurodevelopmental disorders are multi-faceted and can lead to intellectual disability,
autism spectrum disorder and language impairment. Mutations in the Forkhead box FOXP1 …

FOXP2 is a transcription factor containing a polyglutamine tract, a zinc-finger motif, and a
forkhead DNA-binding domain. The FOXP2 gene is located on 7q31. A missense mutation …

Although a mutation (R553H) in the forkhead box (FOX) P2 gene is associated with
speech/language disorder, little is known about the function of FOXP2 or its relevance to this …

In 2001, scientists characterized the first gene to be implicated in the cause of a speech and
language disorder (FOXP2). Although FOXP2 was discovered using a unique family in …

Autism spectrum disorders (ASD) is a neurodevelopmental disease with complex genetics;
however, the genes that are responsible for this disease still remain mostly unknown. Here …

Mutations in FOXP1, located at 3p13, have been reported in patients with global
developmental delay (GDD), intellectual disability (ID), and speech defects. Mutations in …

FOXP proteins form a subfamily of evolutionarily conserved transcription factors involved in
the development and functioning of several tissues, including the central nervous system. In …

Forkhead-box protein P2 is a transcription factor that has been associated with intriguing
aspects of cognitive function in humans, non-human mammals, and song-learning birds …

The signalling pathways controlling both the evolution and development of language in the
human brain remain unknown. So far, the transcription factor FOXP2 (forkhead box P2) is …

The identification of the first gene involved in a speech-language disorder was made
possible through the study of a British multi-generational family (the “KE family”) in whom …