Carriers of genetic material are divided into vectors of viral and non-viral origin. Viral carriers
are already successfully used in experimental gene therapies, but despite advantages such …

Drug delivery systems for cancer chemotherapy are employed to improve the effectiveness
and decrease the side-effects of highly toxic drugs. Most chemotherapy agents have …

Poly (amidoamine)(PAMAM) dendrimers are promising multipotent gene delivery vectors,
providing favorable DNA condensation properties also in combination with the possibility of …

Dendrimers are nanoscopic compounds, which are monodispersed, and they are generally
considered as homogeneous. PAMAM (polyamidoamine) was introduced in 1985, by …

A new family of gene delivery vectors is synthesized consisting of a medium-size generation
PAMAM dendrimer (generation 5, with amine termini) core randomly linked at the periphery …

Abstract Poly (amidoamine)(PAMAM) dendrimers are well-defined, highly branched
macromolecules with numerous active amine groups on the surface. Because of their …

Abstract Poly (amidoamine)(PAMAM) dendrimers are a novel class of spherical, well-
designed branching polymers with interior cavities and abundant terminal groups on the …

Poly (amidoamine)(PAMAM) dendrimers are the first complete dendrimer family to be
synthesized, characterized and commercialized. Based on this extensive activity, they are …

Abstract Poly (amidoamine) dendrimers (PAMAM) are novel polymeric highly branched
architectures with well-defined nano-size, narrow polydispersity index and numerous active …

Non-viral methods of gene delivery are attractive alternatives compared to virus-based gene
delivery. Polyamidoamine (PAMAM) dendrimers are a new class of highly branched …