Clostridium difficile infection (CDI) became a public health problem for the global spreading
of the so-called hypervirulent PCR ribotypes (RTs) 027 and 078, associated with increases …

Clostridium difficile infection (CDI) represents a great healthcare burden in developed
countries. The emergence of the epidemic PCR ribotype (RT) 027 and its acquired …

Objectives Clostridium difficile is a major global human pathogen divided into five clades, of
which clade 3 is the least characterized and consists predominantly of PCR ribotype (RT) …

Clostridium difficile is a major bacterial cause of post-antibiotic diarrhoea. The epidemiology
of C. difficile infections (CDI) has dramatically changed since the early 2000s, with an …

Epidemiological surveillance of Clostridium difficile infection has gained importance in
recent years as a result of the rapid spread of epidemic strains, including hypervirulent …

Background Clostridium difficile infection (CDI) is a major cause of antibiotic-associated
diarrhoea. Given an increasing CDI incidence and global spread of epidemic ribotypes, a 1 …

Background Characterising the overlap of C. difficile genotypes in different reservoirs can
improve our understanding of possible transmission routes of this pathogen. Most of the …

Global spread and evolutionary links of an epidemic Clostridium difficile strain (PCR-
ribotype 027) have been noted in recent decades. However, in Japan, no outbreaks caused …

Worldwide increasing rates of Clostridium difficile infections (CDI) with severe courses and
outbreaks have been reported. This change in CDI epidemiology has on one hand been …

Background Clostridium difficile is a leading infectious cause of health care associated
diarrhoea. Several industrialised countries have reported increased C. difficile infections …