Superoxide dismutase (SOD) is a major defender against excessive superoxide generated
under hyperglycemia. We have recently reported that renal SOD1 (cytosolic CuZn-SOD) and …

To identify genetic variants associated with diabetic retinopathy (DR), we performed a large
multiethnic genome-wide association study. Discovery included eight European cohorts (n …

Diabetic type 2 patients compared to nondiabetic patients exhibit an increased risk of
developing diabetic kidney disease (DKD), the leading cause of end-stage renal disease …

Purpose.: To investigate whether variants in cardiovascular candidate genes, some of which
have been previously associated with type 2 diabetes (T2D), diabetic retinopathy (DR), and …

A genome-wide association scan of type 1 diabetic patients from the GoKinD collections
previously identified four novel diabetic nephropathy susceptibility loci that have …

Diabetic complications including diabetic nephropathy, retinopathy, and neuropathy are as
major causes of morbidity and mortality in diabetes individuals worldwide and current …

Background The SOD2 gene encodes an antioxidant enzyme, mitochondrial superoxide
dismutase. SOD2 polymorphisms are of interest because of their potential roles in the …

Genetic susceptibility is considered an important factor for the development and progression
to diabetic nephropathy (DN), and for more than 20 years researchers have tried tounravel …

Diabetes is increasing at daunting rates worldwide, and approximately 40% of affected
individuals will develop kidney complications. Diabetic kidney disease (DKD) is the leading …

We investigated the association of signals from previous GWAS and candidate gene meta-
analyses for diabetic retinopathy (DR) or nephropathy (DN), as well as an EPO variant in …