Multi-omics analysis of cancer cell lines with high/low ferroptosis scores and development of a ferroptosis-related model for multiple cancer types
G Shan, H Zhang, G Bi, Y Bian, J Liang… - Frontiers in cell and …, 2021 - frontiersin.org
Background: Ferroptosis is a newly identified regulated cell death characterized by iron-
dependent lipid peroxidation and subsequent membrane oxidative damage, which has …
dependent lipid peroxidation and subsequent membrane oxidative damage, which has …
Systematic analysis of the aberrances and functional implications of ferroptosis in cancer
Ferroptosis is a type of cell death related to cancer; however, the characteristics of
ferroptosis in cancers are still uncertain. Based on the data in The Cancer Genome Atlas, we …
ferroptosis in cancers are still uncertain. Based on the data in The Cancer Genome Atlas, we …
A novel ferroptosis-related genes model for prognosis prediction of lung adenocarcinoma
F Li, D Ge, S Sun - BMC Pulmonary Medicine, 2021 - Springer
Background Ferroptosis is a newly discovered form of cell death characterized by iron-
dependent lipid peroxidation. This study aims to investigate the potential correlation …
dependent lipid peroxidation. This study aims to investigate the potential correlation …
[HTML][HTML] Integrative analysis of the molecular mechanisms, immunological features and immunotherapy response of ferroptosis regulators across 33 cancer types
B Tang, R Yan, J Zhu, S Cheng, C Kong… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Ferroptosis is a recently described mode of cell death caused by the accumulation of
intracellular iron and lipid reactive oxygen species (ROS), which play critical roles in …
intracellular iron and lipid reactive oxygen species (ROS), which play critical roles in …
Construction and validation of a 15-gene ferroptosis signature in lung adenocarcinoma
G Tu, W Peng, Q Cai, Z Zhao, X Peng, B He, P Zhang… - PeerJ, 2021 - peerj.com
Background Ferroptosis is a novel form of programmed cell death characterized by the
excessive accumulation of intracellular iron and an increase in reactive oxygen species …
excessive accumulation of intracellular iron and an increase in reactive oxygen species …
Programming a Ferroptosis‐to‐Apoptosis Transition Landscape Revealed Ferroptosis Biomarkers and Repressors for Cancer Therapy
Ferroptosis and apoptosis are key cell‐death pathways implicated in several human
diseases including cancer. Ferroptosis is driven by iron‐dependent lipid peroxidation and …
diseases including cancer. Ferroptosis is driven by iron‐dependent lipid peroxidation and …
Prognostic role and potential mechanisms of the ferroptosis-related metabolic gene signature in hepatocellular carcinoma
T Dai, J Li, X Lu, L Ye, H Yu, L Zhang… - Pharmacogenomics …, 2021 - Taylor & Francis
Purpose Ferroptosis, as a novel regulated cell death form, has a close interaction with
metabolism, which is largely unknown in cancer. In the present study, we conducted a …
metabolism, which is largely unknown in cancer. In the present study, we conducted a …
Ferroptosis characterization in lung adenocarcinomas reveals prognostic signature with immunotherapeutic implication
S Sun, Y Yang, Z Yang, J Wang, R Li, H Tian… - Frontiers in cell and …, 2021 - frontiersin.org
The iron-dependent cell death named ferroptosis has been implicated in the progression
and therapeutic response of several tumors. However, potential role of ferroptosis in lung …
and therapeutic response of several tumors. However, potential role of ferroptosis in lung …
Multi-omics characterization and therapeutic liability of ferroptosis in melanoma
Ferroptosis, an iron-dependent form of programmed cell death driven by excessive lipid
peroxidation, 1 has emerged as a promising and effective strategy for triggering cancer cell …
peroxidation, 1 has emerged as a promising and effective strategy for triggering cancer cell …
[HTML][HTML] Integrated profiling uncovers prognostic, immunological, and pharmacogenomic features of ferroptosis in triple-negative breast cancer
K Fang, Z Xu, S Jiang, C Yan, D Tang… - Frontiers in …, 2022 - frontiersin.org
Objective Ferroptosis is an iron-dependent type of regulated cell death triggered by the toxic
buildup of lipid peroxides on cell membranes. Nonetheless, the implication of ferroptosis in …
buildup of lipid peroxides on cell membranes. Nonetheless, the implication of ferroptosis in …
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