Conventional adenomas have historically been considered to be the only screening-
relevant colorectal cancer (CRC) precursor lesion. The prevailing paradigm was that most …

Screening and surveillance for colorectal cancer (CRC) reduces mortality through the
detection of early-stage adenocarcinoma, and more importantly the detection and removal of …

A strong evidence base supports colorectal cancer screening. Interruption of the adenoma-
carcinoma sequence by endoscopic polypectomy has been considered the key step in …

BACKGROUND: Serrated polyposis syndrome (SPS) is a rare condition of multiple serrated
colorectal polyps and cancers. Colorectal cancer risk is increased in SPS. OBJECTIVE: We …

Sessile serrated adenoma/polyps (SSA/Ps) are early precursor lesions in the serrated
neoplasia pathway, which results in colorectal carcinomas with BRAF mutations, methylation …

Identification of the serrated neoplasia pathway has improved our understanding of the
pathogenesis of colorectal cancer (CRC). Insights include an increased recognition of the …

Serrated polyps were once thought to have no clinical implications with regards to the
development of colorectal cancer (CRC). Over the past several years, published data have …

Abstract Purpose of Review In this manuscript, we review current surveillance guidelines for
serrated polyps (SPs) and discuss how recent studies inform the selection of appropriate …

Serrated lesions of the colorectum include hyperplastic polyps, which are non-neoplastic,
and sessile serrated adenomas (SSAs, also known as sessile serrated polyps) and …

AIM To compared individuals with serrated polyposis syndrome (SPS) to those with sessile
serrated adenoma (SSA) and adenomas in the setting of endoscopists with high adenoma …