The canonical role of messenger RNA (mRNA) is to deliver protein-coding information to
sites of protein synthesis. However, given that microRNAs bind to RNAs, we hypothesized …

Long noncoding RNAs: the search for function | Nature Methods Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

Significant fractions of eukaryotic genomes give rise to RNA, much of which is unannotated
and has reduced protein-coding potential. The genomic origins and the associations of …

The transcriptomes of eukaryotic cells are incredibly complex. Individual non-coding RNAs
dwarf the number of protein-coding genes, and include classes that are well understood as …

The small nuclear RNAs (snRNAs) are a class of metabolically stable small RNAs present in
the nuclei of eukaryotic cells1. In mammalian cells, there are six major molecular species …

Human U1 small nuclear (sn) RNA, required for splicing of pre-mRNA, is encoded by genes
on chromosome 1 (1p36). Imperfect copies of these U1 snRNA genes, also located on …

ALTHOUGH small nuclear RNAs (snRNAs) have been studied extensively1, 2, almost
nothing is known about how they function in cells. I present here the results of a detailed …

RNA finds a simpler way | Nature Skip to main content Thank you for visiting nature.com. You
are using a browser version with limited support for CSS. To obtain the best experience, we …

Most genetic information is expressed as, and transacted by, proteins. Yet, less than 2% of
the human genome actually codes for proteins, prompting a search for functions for the other …

Long noncoding RNAs (lncRNAs) are emerging as key parts of multiple cellular pathways,
but their modes of action and how these are dictated by sequence remain unclear. lncRNAs …