We have mapped and quantified mouse transcriptomes by deeply sequencing them and
recording how frequently each gene is represented in the sequence sample (RNA-Seq) …

Around 98% of all transcriptional output in humans is non-coding RNA. RNA-mediated gene
regulation is widespread in higher eukaryotes and complex genetic phenomena like RNA …

Increasing numbers of transcripts have been reported to transmit both protein-coding and
regulatory information. Apart from challenging our conception of the gene, this observation …

Structured RNAs embedded in the untranslated regions (UTRs) of messenger RNAs can
regulate gene expression. In bacteria, control of a metabolite gene is mediated by the self …

The expanding world of small RNAs | Nature Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

To the Editor: The majority of the gene variants discovered by nextgeneration sequencing
(NGS) projects are either intronic or synonymous. These variants are difficult to interpret …

Shrinking maps of RNA modifications | Nature Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

THE origin of the RNA world1 is not easily understood, as effective prebiotic syntheses of the
components of RNA, the β-ribofurano-side-5′-phosphates, are hard to envisage2 …

There is growing evidence that mammalian genomes produce thousands of transcripts that
do not encode proteins, and this RNA class might even rival the complexity of mRNAs. There …

Non-coding RNA transcription: turning on neighbours | Nature Cell Biology Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …